SCHEMBL8207250

SCHEMBL8207250

CC(NC(C)c1ccc(Cl)c(Cl)c1)c1ccc(Cl)c(Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
LMNA P02545 1/20 0.56
HTT P42858 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
SLC6A4 P31645 8/20 0.44
SLC6A3 Q01959 7/20 0.44
SLC6A2 P23975 7/20 0.44
AHR P35869 1/20 0.44
ADRB2 P07550 1/20 0.43
CYP1A2 P05177 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KCNH2 Q12809 4/20 0.40
CYP3A4 P08684 4/20 0.40
CYP2D6 P10635 4/20 0.40
CHRM1 P11229 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10315762 0.91 ALDH1A1 (0.53) ALDH1A1LMNAHTTSMN1; SMN2SLC6A4
SCHEMBL10087176 0.91 ALDH1A1 (0.53) ALDH1A1LMNAHTTSMN1; SMN2SLC6A4
SCHEMBL178624 0.84 ALDH1A1 (0.54) ALDH1A1LMNAHTTSMN1; SMN2SLC6A4
SCHEMBL13267449 0.84 ALDH1A1 (0.54) ALDH1A1LMNAHTTSMN1; SMN2SLC6A4
SCHEMBL5862322 0.84 ADRB2 (0.56) ALDH1A1LMNAHTTSMN1; SMN2SLC6A4
SCHEMBL61975 0.84 ADRB2 (0.56) ALDH1A1LMNAHTTSMN1; SMN2SLC6A4
SCHEMBL29453111 0.84 ADRB2 (0.56) ALDH1A1LMNAHTTSMN1; SMN2SLC6A4
SCHEMBL3181409 0.84 ADRB2 (0.56) ALDH1A1LMNAHTTSMN1; SMN2SLC6A4
SCHEMBL11395309 0.83 ALDH1A1 (0.53) ALDH1A1LMNAHTTSMN1; SMN2SLC6A4
Hydrochloric Acid SCHEMBL3704821 0.82 ADRB2 (0.54) ALDH1A1LMNAHTTSMN1; SMN2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6093851-A N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2000-07-25 US disclosed
EP-0735018-B1 N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL CO (JP) 1999-07-21 EP disclosed
US-5739401-A N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-04-14 US disclosed
EP-0735018-A1 N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-02 EP disclosed