Diphenylmethane

Diphenylmethane

SCHEMBL8207255

CC(C)(C)CNC(N)=O.CC(C)(C)CNC(N)=O.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.49
PLA2G10 O15496 1/20 0.49
PLA2G2A P14555 1/20 0.49
TACR3 P29371 1/20 0.48
LMNA P02545 3/20 0.44
RIPK1 Q13546 1/20 0.42
MAPT P10636 3/20 0.41
RAB9A P51151 2/20 0.41
POLB P06746 1/20 0.41
NPC1 O15118 1/20 0.41
CALM1 P0DP23 1/20 0.41
BCAT2 O15382 1/20 0.41
ALDH1A1 P00352 2/20 0.41
USP2 O75604 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
RECQL P46063 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MTNR1A P48039 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL8210901 0.84 LMNA (0.44) LMNAMAPTRAB9APOLBNPC1
Diphenylmethane SCHEMBL28763067 0.80 PLA2G10 (0.53) PLA2G10PLA2G2ALMNARIPK1NPC1
SCHEMBL74035 0.79
Diphenylmethane SCHEMBL27952621 0.75 PLA2G10 (0.61) PLA2G10PLA2G2ALMNACALM1MEN1
SCHEMBL9517017 0.75 MAPT (0.50) LMNAMAPTBCAT2KMT2A
SCHEMBL13701830 0.75 MEN1 (0.55) LMNAMAPTRAB9ANPC1ALDH1A1
Diphenylmethane SCHEMBL18604552 0.74 PLA2G10 (0.71) PLA2G10PLA2G2ALMNAMAPTPOLB
Diphenylmethane SCHEMBL8743340 0.74 PLA2G10 (0.71) PLA2G10PLA2G2ALMNAMAPTPOLB
Diphenylmethane SCHEMBL28144267 0.74 PLA2G10 (0.71) PLA2G10PLA2G2ALMNAMAPTPOLB
Diphenylmethane SCHEMBL10451543 0.74 PLA2G10 (0.71) PLA2G10PLA2G2ALMNAMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0986536-A1 METHOD FOR THE PREPARATION OF ORGANIC ISOCYANATES HUNTSMAN ICI CHEMICALS LLC (US) 2000-03-22 EP disclosed
WO-1998054129-A1 METHOD FOR THE PREPARATION OF ORGANIC ISOCYANATES HUNTSMAN ICI CHEMICALS LLC (US) 1998-12-03 WO disclosed