SCHEMBL8207273

SCHEMBL8207273

CC(C)C(N)c1ccc(Cl)cc1Cl

nearest known ligand 0.70

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.70
LMNA P02545 1/20 0.70
HTT P42858 1/20 0.70
ESR1 P03372 1/20 0.48
IDO1 P14902 1/20 0.42
TDO2 P48775 1/20 0.42
TSHR P16473 3/20 0.41
CYP3A4 P08684 1/20 0.41
ADRB2 P07550 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
EPHX1 P07099 1/20 0.37
PNMT P11086 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MC4R P32245 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A3 Q01959 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7784770 0.87 TP53 (0.68) TP53LMNAHTTESR1IDO1
SCHEMBL5492924 0.83 TP53 (1.00) TP53LMNAHTTESR1IDO1
SCHEMBL29723016 0.83 TP53 (1.00) TP53LMNAHTTESR1IDO1
SCHEMBL30542082 0.83 TP53 (1.00) TP53LMNAHTTESR1IDO1
SCHEMBL3899828 0.83 TP53 (1.00) TP53LMNAHTTESR1IDO1
SCHEMBL3317981 0.83 TP53 (1.00) TP53LMNAHTTESR1IDO1
Hydrochloric Acid SCHEMBL27636481 0.81 LMNA (0.96) TP53LMNAHTTESR1IDO1
Hydrochloric Acid SCHEMBL1884136 0.81 LMNA (0.96) TP53LMNAHTTESR1IDO1
Hydrochloric Acid SCHEMBL27636482 0.81 LMNA (0.96) TP53LMNAHTTESR1IDO1
SCHEMBL18994860 0.78 TP53 (0.63) TP53LMNAHTTIDO1TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6093851-A N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2000-07-25 US disclosed
EP-0735018-B1 N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL CO (JP) 1999-07-21 EP disclosed
US-5739401-A N-(α-alkylbenzylidene)-α-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-04-14 US disclosed
EP-0735018-A1 N-(alpha-alkylbenzylidene)-alpha-phenylalkylamine, its use and process for producing the same and process for producing intermediate therefor SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-02 EP disclosed