Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 2/20 | 0.34 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207424 | 1.00 | PPM1D (0.34) | PPM1DCDC25ACDC25B | |
| SCHEMBL8210922 | 0.94 | CDC25A (0.38) | PPM1DCDC25ACDC25B | |
| SCHEMBL8247464 | 0.94 | CDC25A (0.38) | PPM1DCDC25ACDC25B | |
| SCHEMBL8255934 | 0.94 | CDC25A (0.38) | PPM1DCDC25ACDC25B | |
| SCHEMBL8210861 | 0.94 | CDC25A (0.38) | PPM1DCDC25ACDC25B | |
| SCHEMBL7144078 | 0.85 | CDC25A (0.35) | PPM1DCDC25ACDC25B | |
| SCHEMBL7144084 | 0.85 | CDC25A (0.35) | PPM1DCDC25ACDC25B | |
| SCHEMBL8359281 | 0.84 | CDC25A (0.38) | PPM1DCDC25ACDC25B | |
| SCHEMBL8359283 | 0.84 | CDC25A (0.38) | PPM1DCDC25ACDC25B | |
| SCHEMBL8359286 | 0.84 | CDC25A (0.38) | PPM1DCDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153605-A | Arylsecocholadiene derivatives | HOFFMAN-LA ROCHE INC. (US) | 2000-11-28 | — | — | US | disclosed |