Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12677791 | 0.94 | ALDH1A1 (0.45) | ALDH1A1TSHRDNM1TDP1CA12 | |
| SCHEMBL12621130 | 0.89 | ALDH1A1 (0.41) | ALDH1A1TSHRDNM1TDP1CYP1A2 | |
| SCHEMBL3891202 | 0.84 | TDP1 (0.41) | ALDH1A1TSHRDNM1TDP1CYP1A2 | |
| SCHEMBL8928256 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRDNM1TDP1CA12 | |
| SCHEMBL12677793 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TSHRDNM1TDP1CA12 | |
| Hydrochloric Acid SCHEMBL28914158 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TSHRDNM1TDP1CA12 | |
| SCHEMBL2503595 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TSHRDNM1 | |
| SCHEMBL3777474 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TSHRDNM1TDP1CA12 | |
| SCHEMBL21741888 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TSHRDNM1TDP1CA12 | |
| SCHEMBL19861866 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TSHRDNM1TDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10287683-A | — | — | None | — | — | JP | disclosed |
| US-20180112015-A1 | POLYMERIZATION INITIATOR, MODIFIED CONJUGATED DIENE-BASED POLYMER, AND METHODS FOR PREPARING THEM | LG CHEM, LTD. (KR) | 2018-04-26 | — | — | US | disclosed |
| US-8273726-B2 | Compositions for treating and/or preventing diseases characterized by the presence of metal ions | BRANDEIS UNIVERSITY (US) | 2012-09-25 | — | — | US | disclosed |
| US-20100184724-A1 | COMPOSITIONS FOR TREATING AND/OR PREVENTING DISEASES CHARACTERIZED BY THE PRESENCE OF METAL IONS | GRENPHARMA LLC (US) | 2010-07-22 | — | — | US | disclosed |
| US-7595308-B2 | Treatment and/or prevention of Alzheimer's disease, other neurodegenerative diseases, and/or diseases characterized by the presence of certain metal ions, by using organosilicon compounds such as dichlorodiethylsilane | GRENPHARMA LLC (US) | 2009-09-29 | — | — | US | disclosed |
| US-20090203644-A1 | Compositions for treating and/or preventing diseases characterized by the presence of metal ions | GRENPHARMA LLC (US) | 2009-08-13 | — | — | US | disclosed |
| US-6120962-A | TONERS FOR DEVELOPMENT OF LATENT IMAGES | RICOH COMPANY, LTD. (JP) | 2000-09-19 | — | — | US | disclosed |
| JP-H10287683-A | NOVEL ORGANOSILICON COMPOUND, ITS PRODUCTION, AND STATIC CHARGE IMAGE-DEVELOPING TONER, AND DRY IMAGE DEVELOPER USING THE SAME | RICOH CO LTD | 1998-10-27 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184724-A1 | COMPOSITIONS FOR TREATING AND/OR PREVENTING DISEASES CHARACTERIZED BY THE PRESENCE OF METAL IONS | FABP2, SLC3A2, SLC40A1 | ALDH1A1 1931/4885TSHR 1785/4885DNM1 1114/4885 |
| US-20180112015-A1 | POLYMERIZATION INITIATOR, MODIFIED CONJUGATED DIENE-BASED POLYMER, AND METHODS FOR PREPARING THEM | RIF1, RAD51, TRRAP | ALDH1A1 517/4885TSHR 3880/4885DNM1 1630/4885 |
| US-20090203644-A1 | Compositions for treating and/or preventing diseases characterized by the presence of metal ions | APP, PSEN1, IAPP | ALDH1A1 4682/4885TSHR 3968/4885DNM1 788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.