Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7708877 | 0.77 | NPC1 (0.41) | CTSA | |
| SCHEMBL8207539 | 0.70 | PTGDR2 (0.35) | BRS3 | |
| SCHEMBL8185758 | 0.69 | CTSA (0.40) | CTSABRS3 | |
| SCHEMBL7240383 | 0.69 | FNTA (0.41) | CTSA | |
| SCHEMBL7856745 | 0.67 | BRS3 (0.39) | BRS3 | |
| SCHEMBL8210369 | 0.65 | BRS3 (0.46) | BRS3 | |
| SCHEMBL6775461 | 0.64 | PTPN1 (0.56) | — | |
| SCHEMBL10909137 | 0.62 | PTPN1 (0.53) | — | |
| SCHEMBL6679972 | 0.62 | PTPN1 (0.53) | — | |
| SCHEMBL6777102 | 0.62 | PTPN1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | disclosed |