Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2926429 | 0.76 | HTT (0.41) | HTTALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL13786724 | 0.76 | TSHR (0.35) | SMN1; SMN2 | |
| SCHEMBL11122001 | 0.75 | TSHR (0.41) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL35709 | 0.71 | — | — | |
| SCHEMBL21570869 | 0.71 | TSHR (0.48) | ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL278037 | 0.71 | — | — | |
| SCHEMBL24687424 | 0.71 | HTT (0.48) | HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL965595 | 0.71 | HTT (0.48) | HTTALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL42473 | 0.71 | ALDH1A1 (0.59) | HTTALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL11173967 | 0.71 | HTT (0.48) | HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396364-B1 | Copolymers of vinyl carbonate and vinyl carbamate as contact lens material | BAUSCH & LOMB (US) | 1997-06-11 | — | — | EP | claimed |
| US-5610252-A | Vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 1997-03-11 | — | — | US | claimed |
| EP-0396364-A2 | Novel vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 1990-11-07 | — | — | EP | claimed |
| US-6166236-A | Vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 2000-12-26 | — | — | US | disclosed |
| EP-0559820-B1 | SURFACE COATING OF POLYMER OBJECTS | BAUSCH & LOMB (US) | 1998-02-18 | — | — | EP | disclosed |
| EP-0396364-B1 | Copolymers of vinyl carbonate and vinyl carbamate as contact lens material | BAUSCH & LOMB (US) | 1997-06-11 | — | — | EP | disclosed |
| US-5610252-A | Vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 1997-03-11 | — | — | US | disclosed |
| EP-0560916-B1 | Method of molding of silicon-containing contact lenses | BAUSCH & LOMB (US) | 1997-02-05 | — | — | EP | disclosed |
| EP-0559809-B1 | SURFACE MODIFICATION OF POLYMER OBJECTS | BAUSCH & LOMB (US) | 1996-11-06 | — | — | EP | disclosed |
| CN-1032909-C | Mold materials for silicone containing lens materials | BAUSCH & LOMB (US) | 1996-10-02 | — | — | CN | disclosed |
| EP-0559784-B1 | SURFACE-ACTIVE MACROMONOMERS | BAUSCH & LOMB (US) | 1996-08-21 | — | — | EP | disclosed |
| US-5158717-A | Contact lenses from copolymerizing silicone and hydrophilic monomers in mold produced from an acrylonitrile copolymer resin; melt processability, wettability | BAUSCH & LOMB INCORPORATED (US) | 1992-10-27 | — | — | US | disclosed |
| US-5135297-A | Immersing a contact lens in an aqueous dispersion of a polymerizable surfactant macromer, a crosslinker and a free radical catalyst and irradiating with UV light; wetting agents | BAUSCH & LOMB INCORPORATED (US) | 1992-08-04 | — | — | US | disclosed |
| CN-1061931-A | Contain the mold materials that the siloxane lens materials is used | BAUSCH & LOMB (US) | 1992-06-17 | — | — | CN | disclosed |
| WO-1992009639-A2 | SURFACE-ACTIVE MACROMONOMERS | BAUSCH & LOMB INCORPORATED (US) | 1992-06-11 | — | — | WO | disclosed |
| WO-1992009650-A1 | SURFACE COATING OF POLYMER OBJECTS | BAUSCH & LOMB INCORPORATED (US) | 1992-06-11 | — | — | WO | disclosed |
| WO-1992009644-A1 | SURFACE MODIFICATION OF POLYMER OBJECTS | BAUSCH & LOMB INCORPORATED (US) | 1992-06-11 | — | — | WO | disclosed |
| WO-1992009421-A2 | MOLD MATERIALS FOR SILICONE CONTAINING LENS MATERIALS | BAUSCH & LOMB INCORPORATED (US) | 1992-06-11 | — | — | WO | disclosed |
| US-5070215-A | Gas permeable contact lenses | BAUSCH & LOMB INCORPORATED (US) | 1991-12-03 | — | — | US | disclosed |
| EP-0396364-A2 | Novel vinyl carbonate and vinyl carbamate contact lens material monomers | BAUSCH & LOMB INCORPORATED (US) | 1990-11-07 | — | — | EP | disclosed |