Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Dimethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL8208191 | 0.99 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HTTLMNACYP2C9 | |
| Hexanoate SCHEMBL8583304 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNACYP2C9TDP1ALB | |
| Octane SCHEMBL356741 | 0.81 | MCHR1 (0.56) | ALDH1A1L3MBTL1HTTLMNACYP2C9 | |
| Heptane SCHEMBL8501523 | 0.81 | MCHR1 (0.56) | ALDH1A1L3MBTL1HTTLMNACYP2C9 | |
| Nonane SCHEMBL27767997 | 0.81 | MCHR1 (0.56) | ALDH1A1L3MBTL1HTTLMNACYP2C9 | |
| Decane SCHEMBL17004268 | 0.81 | MCHR1 (0.56) | ALDH1A1L3MBTL1HTTLMNACYP2C9 | |
| Octane SCHEMBL8462698 | 0.81 | MCHR1 (0.56) | ALDH1A1L3MBTL1HTTLMNACYP2C9 | |
| Dodecane SCHEMBL7126605 | 0.81 | MCHR1 (0.56) | ALDH1A1L3MBTL1HTTLMNACYP2C9 | |
| Heptane SCHEMBL27143738 | 0.81 | MCHR1 (0.56) | ALDH1A1L3MBTL1HTTLMNACYP2C9 | |
| Heptanamide SCHEMBL12520449 | 0.80 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1HTTLMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988283-A2 | PEROXYACIDS | UNILEVER PLC (GB) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998056760-A1 | PEROXYACIDS | UNILEVER PLC (GB) | 1998-12-17 | — | — | WO | disclosed |