Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | FLT3 | P36888 | 2/20 | 0.50 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200087 | 0.91 | KDM4E (0.56) | CNR2CNR1HSD17B10SMN1; SMN2KDM4E | |
| Bicarbonate SCHEMBL7421513 | 0.90 | ALDH1A1 (0.56) | CNR2CNR1HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL8207571 | 0.85 | CNR2 (0.58) | CNR2CNR1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL8206909 | 0.85 | RORC (0.63) | CNR2CNR1HSD17B10SMN1; SMN2KDM4E | |
| SCHEMBL8212606 | 0.84 | CNR2 (0.61) | CNR2CNR1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL8212352 | 0.83 | CNR2 (0.55) | CNR2CNR1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL8207640 | 0.83 | KDM4E (0.65) | HSD17B10SMN1; SMN2KDM4EALDH1A1TSHR | |
| SCHEMBL8200143 | 0.82 | PKM (0.52) | HSD17B10SMN1; SMN2KDM4EKMT2AMEN1 | |
| SCHEMBL8200015 | 0.82 | PKM (0.52) | HSD17B10SMN1; SMN2KDM4EALDH1A1KMT2A | |
| SCHEMBL8200351 | 0.82 | CNR2 (0.54) | CNR2CNR1HSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |