SCHEMBL8207704

SCHEMBL8207704

CCOC(=O)c1ccc(OC(=O)c2ccc(Cl)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.61
ACR P10323 1/20 0.61
KMT2A Q03164 5/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
MEN1 O00255 2/20 0.59
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
ESR1 P03372 1/20 0.56
CA7 P43166 1/20 0.56
CA9 Q16790 1/20 0.56
ESR2 Q92731 1/20 0.56
CA14 Q9ULX7 1/20 0.56
CYP1A2 P05177 3/20 0.54
CYP3A4 P08684 2/20 0.54
LMNA P02545 1/20 0.54
MAOA P21397 1/20 0.54
STS P08842 1/20 0.54
MAPT P10636 3/20 0.51
CYP2C9 P11712 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10344282 0.91 PRSS1 (0.69) PRSS1ACRKMT2AMEN1CA12
SCHEMBL203843 0.89 CA12 (0.68) KMT2ASMN1; SMN2MEN1CA12CA1
SCHEMBL8205439 0.86 PRSS1 (0.64) PRSS1ACRKMT2AMEN1CA12
SCHEMBL14029067 0.86 LMNA (0.62) KMT2ASMN1; SMN2MEN1ESR1CYP1A2
SCHEMBL610755 0.86 KMT2A (0.69) PRSS1KMT2ASMN1; SMN2MEN1CYP1A2
SCHEMBL10599787 0.86 KMT2A (0.69) PRSS1KMT2ASMN1; SMN2MEN1CYP1A2
SCHEMBL9683516 0.86 KMT2A (0.69) PRSS1KMT2ASMN1; SMN2MEN1CYP1A2
SCHEMBL28003430 0.86 KMT2A (0.69) PRSS1KMT2ASMN1; SMN2MEN1CYP1A2
SCHEMBL8205737 0.85 PRSS1 (0.62) PRSS1ACRKMT2ASMN1; SMN2MEN1
SCHEMBL6938102 0.85 ESR1 (0.79) PRSS1ACRKMT2ASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6117562-A A THERMAL IMAGE TRANSFER INK LAYER FORMED ON THE SUPPORT; INK LAYER COMPRISING A COLORING AGENT, A RESIN AND A PLASTICIZER FOR LOWERING THE MELT VISCOSITY OF RESIN RICOH COMPANY, LTD. (JP) 2000-09-12 US disclosed
US-4609928-A LEUCO DYES, COLOR DEVELOPERS, BISHENOL, P-HYDROXYBENZOIC ACID ESTER, POROSITY, FILLERS RICOH COMPANY, LTD. (JP) 1986-09-02 US disclosed
US-4575734-A LEVCO DYES RICOH COMPANY, LTD. (JP) 1986-03-11 US disclosed
US-4562448-A Heat-sensitive transfer medium RICOH CO., LTD. (JP) 1985-12-31 US disclosed
US-4547788-A SHEET HAVING LAYER CONTAINING LEVCO DYE; ACCEPTOR SHEET CONTAININGCOLORING AGENT; POROUS FILLER RICOH COMPANY, LTD. (JP) 1985-10-15 US disclosed
US-4444844-A LEUCO DYE, SPECIFIC PHENYL BENZOATES AS DEVELOPER AND PROMOTER, FOR HIGH SPEED AND DENSITY RICOH CO., LTD. (JP) 1984-04-24 US disclosed