Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | FBP1 | P09467 | 9/20 | 0.49 |
| ▸ | F2 | P00734 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7379009 | 0.86 | KMT2A (0.49) | KMT2AFBP1F2 | |
| Hydrochloric Acid SCHEMBL7704939 | 0.85 | KMT2A (0.48) | KMT2AFBP1F2 | |
| Hydrochloric Acid SCHEMBL7844930 | 0.85 | KMT2A (0.48) | KMT2AFBP1F2 | |
| SCHEMBL7064310 | 0.85 | ALDH1A1 (0.64) | KMT2APOLBFBP1ALDH1A1CYP2C19 | |
| SCHEMBL4795952 | 0.85 | POLB (0.50) | KMT2APOLBFBP1F2ALDH1A1 | |
| SCHEMBL4795962 | 0.85 | POLB (0.50) | KMT2APOLBFBP1F2ALDH1A1 | |
| SCHEMBL6500230 | 0.84 | MMP2 (0.61) | ALDH1A1 | |
| SCHEMBL383079 | 0.84 | MMP2 (0.61) | ALDH1A1 | |
| SCHEMBL8088655 | 0.83 | SLC1A3 (0.64) | FBP1 | |
| SCHEMBL4041728 | 0.82 | TDP1 (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | claimed |
| WO-2000043793-A1 | A FACS METHOD FOR DETECTION OF GPIIb/IIIa INHIBITOR DEPENDENT ACTIVATORS IN PLASMA SAMPLES | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-07-27 | — | — | WO | disclosed |
| US-5849736-A | Isoxazoline and isoxazole fibrinogen receptor antagonists | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-12-15 | — | — | US | disclosed |