Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 14/20 | 0.53 |
| ▸ | MMP1 | P03956 | 13/20 | 0.53 |
| ▸ | MMP7 | P09237 | 14/20 | 0.51 |
| ▸ | MMP13 | P45452 | 9/20 | 0.51 |
| ▸ | MMP2 | P08253 | 6/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211350 | 0.85 | MMP3 (0.57) | MMP3MMP1MMP7MMP13MMP2 | |
| SCHEMBL8199903 | 0.82 | MMP1 (0.61) | MMP3MMP1MMP7MMP13MMP2 | |
| SCHEMBL8199899 | 0.82 | MMP1 (0.61) | MMP3MMP1MMP7MMP13MMP2 | |
| SCHEMBL9865528 | 0.81 | MCOLN3 (0.50) | MMP1MMP13MMP2L3MBTL1 | |
| SCHEMBL9380136 | 0.81 | MCOLN3 (0.50) | MMP1MMP13MMP2L3MBTL1 | |
| SCHEMBL9211270 | 0.81 | MCOLN3 (0.50) | MMP1MMP13MMP2L3MBTL1 | |
| SCHEMBL9684628 | 0.81 | MCOLN3 (0.50) | MMP1MMP13MMP2L3MBTL1 | |
| SCHEMBL2389473 | 0.81 | MCOLN3 (0.50) | MMP1MMP13MMP2L3MBTL1 | |
| SCHEMBL2389980 | 0.81 | MCOLN3 (0.50) | MMP1MMP13MMP2L3MBTL1 | |
| SCHEMBL9685672 | 0.81 | MCOLN3 (0.50) | MMP1MMP13MMP2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121272-A | Bidentate metalloprotease inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-19 | — | — | US | disclosed |