Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.45 |
| ▸ | CCR2 | P41597 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14255658 | 1.00 | SLC6A3 (0.45) | SLC6A3CCR2SLC6A4FFAR1OPRM1 | |
| SCHEMBL8216816 | 1.00 | SLC6A3 (0.45) | SLC6A3CCR2SLC6A4FFAR1OPRM1 | |
| SCHEMBL8218564 | 0.83 | SLC6A4 (0.46) | SLC6A3CCR2SLC6A4OPRM1SLC6A2 | |
| SCHEMBL8215573 | 0.83 | SLC6A4 (0.46) | SLC6A3CCR2SLC6A4OPRM1SLC6A2 | |
| SCHEMBL4728513 | 0.83 | SLC6A4 (0.46) | SLC6A3CCR2SLC6A4OPRM1SLC6A2 | |
| SCHEMBL29302947 | 0.81 | HSD11B1 (0.42) | SLC6A3CCR2SLC6A4FFAR1SLC6A2 | |
| SCHEMBL29879558 | 0.81 | HSD11B1 (0.42) | SLC6A3CCR2SLC6A4FFAR1SLC6A2 | |
| Lithium Ion SCHEMBL29136989 | 0.79 | HSD11B1 (0.40) | SLC6A3CCR2SLC6A4FFAR1SLC6A2 | |
| SCHEMBL14520917 | 0.77 | HSD11B1 (0.40) | CCR2FFAR1OPRM1 | |
| SCHEMBL28266831 | 0.76 | SLC6A3 (0.50) | SLC6A3CCR2SLC6A4SLC6A2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080058535-A1 | METHODS AND COMPOSITIONS FOR PRODUCTION, FORMULATION AND USE OF 1 ARYL-3-AZABICYCLO[3.1.0]HEXANES | DOV PHARMACEUTICAL, INC. | 2008-03-06 | — | — | US | disclosed |
| US-20080058535-A1 | METHODS AND COMPOSITIONS FOR PRODUCTION, FORMULATION AND USE OF 1 ARYL-3-AZABICYCLO[3.1.0]HEXANES | DOV PHARMACEUTICAL, INC. | 2008-03-06 | — | — | US | disclosed |
| WO-2008013856-A2 | METHODS AND COMPOSITIONS FOR PRODUCTION, FORMULATION AND USE OF 1 ARYL -3-AZABICYCLO[3.1.0 ] HEXANES | DOV PHARMACEUTICAL, INC. (US) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058535-A1 | METHODS AND COMPOSITIONS FOR PRODUCTION, FORMULATION AND USE OF 1 ARYL-3-AZABICYCLO[3.1.0]HEXANES | CYP1B1, CYP2B6, CYP2D6 | SLC6A3 982/4885CCR2 372/4885SLC6A4 2230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.