SCHEMBL8208300

SCHEMBL8208300

N#CC(F)c1cc(F)c(F)c(F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7633385 0.77
SCHEMBL7189909 0.74
SCHEMBL28671392 0.74
SCHEMBL15936029 0.74
SCHEMBL3417704 0.73
SCHEMBL2395260 0.70
SCHEMBL7029777 0.70
SCHEMBL7872543 0.70 CES2 (0.32)
SCHEMBL28263200 0.70
SCHEMBL1201615 0.70 CES2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111253396-B Organic compound, mixture, composition, high polymer and application 广州追光科技有限公司 2022-05-27 CN disclosed
CN-112552223-A Organic compound containing oxygenated heterocycle and application thereof 广州华睿光电材料有限公司 2021-03-26 CN disclosed
CN-111253396-A Organic compound, mixture, composition, high polymer and application 杨曦 2020-06-09 CN disclosed
EP-0983276-A1 NOVEL PHOTOCHROMIC SPIROOXAZINE COMPOUNDS, THEIR USE IN OPHTHALMIC OPTICS Transitions Optical, Inc. (US) 2000-03-08 EP disclosed
WO-1998050388-A1 NOVEL PHOTOCHROMIC SPIROOXAZINE COMPOUNDS, THEIR USE IN OPHTHALMIC OPTICS TRANSITIONS OPTICAL INC. (DE) 1998-11-12 WO disclosed