Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22193933 | 0.82 | MEN1 (0.39) | MEN1ALDH1A1KMT2A | |
| SCHEMBL11668112 | 0.72 | MEN1 (0.33) | MEN1ALDH1A1KMT2A | |
| SCHEMBL11667978 | 0.72 | MEN1 (0.33) | MEN1ALDH1A1KMT2A | |
| SCHEMBL822318 | 0.72 | GRIN1 (0.57) | MEN1ALDH1A1KMT2A | |
| SCHEMBL11668171 | 0.70 | ALDH1A1 (0.49) | MEN1ALDH1A1KMT2A | |
| SCHEMBL1931239 | 0.68 | MEN1 (0.55) | MEN1KMT2A | |
| SCHEMBL22193935 | 0.66 | — | — | |
| SCHEMBL821936 | 0.65 | GRIN2D (0.46) | MEN1ALDH1A1KMT2A | |
| SCHEMBL1116036 | 0.62 | MEN1 (0.30) | MEN1ALDH1A1KMT2A | |
| SCHEMBL2480001 | 0.60 | GRIN1 (0.65) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389351-A1 | A PROCESS FOR PREPARING MEMANTINE | Merz Pharma GmbH & Co. KGaA (DE) | 2011-11-30 | — | — | EP | disclosed |
| US-8041802-B2 | Decoupled logical and physical data storage within a database management system | TERADATA US, INC. (US) | 2011-10-18 | — | — | US | disclosed |
| WO-2010083996-A1 | A PROCESS FOR PREPARING MEMANTINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-07-29 | — | — | WO | disclosed |