Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 5/20 | 0.65 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.65 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.65 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.65 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.65 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.65 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1072142 | 0.81 | GRIN1 (0.71) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL8061377 | 0.81 | GRIN1 (0.71) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL292343 | 0.79 | GRIN1 (1.00) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| Hydrochloric Acid SCHEMBL11656535 | 0.77 | GRIN1 (0.95) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL5270620 | 0.77 | GRIN1 (0.65) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL812216 | 0.77 | GRIN1 (0.68) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL13028840 | 0.76 | GRIN1 (0.63) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| Ammonia Solution, Strong SCHEMBL14695768 | 0.74 | GRIN1 (0.65) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL292647 | 0.74 | GRIN1 (1.00) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B | |
| SCHEMBL6064803 | 0.74 | GRIN1 (0.61) | GRIN1GRIN2AGRIN2DGRIN3BGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373612-A1 | METHOD FOR PRODUCING MEMANTINE | Merz Pharma GmbH & Co. KGaA (DE) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010069555-A1 | METHOD FOR PRODUCING MEMANTINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-24 | — | — | WO | disclosed |
| US-20060173215-A1 | Process for the preparation of 1-amino-3,5-dimethyladamantane hydrochloride | TEVA PHARMACEUTICALS USA, INC. | 2006-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173215-A1 | Process for the preparation of 1-amino-3,5-dimethyladamantane hydrochloride | HTR5A, HNMT, HTR1A | GRIN1 56/4885GRIN2A 42/4885GRIN2D 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.