SCHEMBL820849

SCHEMBL820849

CC1(C)OC(=O)C(=O)OC1=O

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.32
TP53 P04637 3/20 0.30
CYP3A4 P08684 3/20 0.30
MAPK1 P28482 3/20 0.30
HIF1A Q16665 2/20 0.30
CYP1A2 P05177 2/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
NPC1 O15118 2/20 0.30
RAB9A P51151 2/20 0.30
NFKB1 P19838 1/20 0.30
THPO P40225 1/20 0.30
PPM1B O75688 1/20 0.30
PTPN1 P18031 1/20 0.30
PPP1CC P36873 1/20 0.30
TFPI2 P48307 1/20 0.30
PPP5C P53041 1/20 0.30
PPP2CA P67775 1/20 0.30
PPP1CA P62136 1/20 0.30
KDM4E B2RXH2 1/20 0.30
GMNN O75496 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7637933 0.78
SCHEMBL4020219 0.74
SCHEMBL17603303 0.72 PTPN1 (0.33) LMNAPTPN1MEN1KMT2A
SCHEMBL599372 0.72 LMNA (0.39) LMNATP53CYP3A4MAPK1HIF1A
SCHEMBL23214498 0.70
SCHEMBL10601533 0.69 HTT (0.33) LMNANFKB1KDM4EMAPTTDP1
SCHEMBL9730908 0.65
SCHEMBL12121173 0.63
SCHEMBL3744775 0.61 CTSD (0.32) LMNA
SCHEMBL13092048 0.59 PTPN1 (0.31) LMNATP53MAPK1PTPN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9200109-B2 Biodegradable adhesive compositions YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) 2015-12-01 US disclosed
EP-2334345-B1 NOVEL BIODEGRADABLE ADHESIVE COMPOSITIONS YISSUM RES DEV CO (IL) 2014-07-23 EP disclosed
US-20110269870-A1 NOVEL BIODEGRADABLE ADHESIVE COMPOSITIONS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD (IL) 2011-11-03 US disclosed
EP-2334345-A2 NOVEL BIODEGRADABLE ADHESIVE COMPOSITIONS Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2011-06-22 EP disclosed
WO-2010026590-A2 NOVEL BIODEGRADABLE ADHESIVE COMPOSITIONS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD (IL) 2010-03-11 WO disclosed
US-20080063620-A1 Novel reverse thermo-sensitive block copolymers YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM 2008-03-13 US disclosed
US-20050008609-A1 Multi-component reverse thermo-sensitive polymeric systems YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM HI TECH PARK, THE HEBREW 2005-01-13 US disclosed
US-20030082235-A1 Novel reverse thermo-sensitive block copolymers YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM 2003-05-01 US disclosed
WO-2003017972-A2 MULTI-COMPONENT POLYMERIC SYSTEMS WITH REVERSE THERMAL GELATION BEHAVIOUR (E.G. PEO-PPO COPOLYMERS) YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2003-03-06 WO disclosed