Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219523 | 0.92 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9225102 | 0.89 | CA1 (0.41) | ALDH1A1THRBTSHRTDP1CA1 | |
| SCHEMBL14444688 | 0.85 | CA1 (0.47) | CA1FDPS | |
| SCHEMBL8218550 | 0.83 | THRB (0.38) | KMT2ATHRBKDM4EMAPK1HIF1A | |
| SCHEMBL11158627 | 0.82 | HDAC1 (0.43) | SMN1; SMN2ALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL8207610 | 0.82 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL18155249 | 0.80 | THRB (0.38) | SMN1; SMN2ALDH1A1THRBCYP3A4TP53 | |
| SCHEMBL9227178 | 0.80 | CA1 (0.44) | ALDH1A1TSHRTDP1CA1CYP3A4 | |
| SCHEMBL14410129 | 0.80 | HTT (0.52) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10580596 | 0.80 | THRB (0.36) | SMN1; SMN2ALDH1A1THRBTSHRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580308-B1 | Working fluid composition for refrigeration machine | KAO CORP (JP) | 2000-11-15 | — | — | EP | disclosed |
| US-5395544-A | Ester-containing working fluid composition for refrigerating machine | KAO CORPORATION (JP) | 1995-03-07 | — | — | US | disclosed |
| EP-0580308-A1 | Working fluid composition for refrigeration machine | KAO CORPORATION (JP) | 1994-01-26 | — | — | EP | disclosed |