Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8208714 | 0.80 | SMN1; SMN2 (0.39) | THRBALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL18155321 | 0.80 | ACHE (0.35) | ACHEALDH1A1 | |
| SCHEMBL9225102 | 0.77 | CA1 (0.41) | THRBALDH1A1CYP3A4MAPK1 | |
| SCHEMBL2531270 | 0.76 | ACHE (0.41) | ACHEALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL8218550 | 0.76 | THRB (0.38) | THRBMAPK1HIF1A | |
| SCHEMBL17640842 | 0.76 | CYP1A2 (0.33) | THRB | |
| SCHEMBL12893358 | 0.76 | TSHR (0.38) | ACHEALDH1A1 | |
| SCHEMBL14444688 | 0.75 | CA1 (0.47) | — | |
| SCHEMBL13668222 | 0.74 | THRB (0.41) | THRBACHEALDH1A1TP53CYP3A4 | |
| SCHEMBL2528932 | 0.73 | ACHE (0.47) | THRBACHEALDH1A1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469737-B2 | Robust polymeric membrane | PALL CORPORATION (US) | 2016-10-18 | — | — | US | disclosed |