Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1686176 | 0.85 | CYP1A2 (0.43) | MEN1LMNAKMT2ATDP1CYP1A2 | |
| Hexylene Glycol SCHEMBL7567869 | 0.80 | MEN1 (0.46) | MEN1LMNAKMT2ATDP1CYP1A2 | |
| SCHEMBL6630327 | 0.80 | MEN1 (0.50) | MEN1LMNAKMT2ATSHRALDH1A1 | |
| Tromethamine SCHEMBL8334055 | 0.80 | LMNA (0.59) | MEN1LMNAKMT2ATDP1CYP1A2 | |
| Tromethamine SCHEMBL7567125 | 0.79 | LMNA (0.67) | MEN1LMNAKMT2ATDP1TSHR | |
| Tromethamine SCHEMBL9547767 | 0.78 | MEN1 (0.56) | MEN1LMNAKMT2ATDP1CYP1A2 | |
| SCHEMBL11725261 | 0.78 | TSHR (0.40) | TDP1CYP1A2CYP3A4CYP2C9HIF1A | |
| SCHEMBL610776 | 0.78 | CYP1A2 (0.39) | TDP1CYP1A2CYP3A4CYP2C9HIF1A | |
| SCHEMBL5972431 | 0.78 | TSHR (0.40) | TDP1CYP1A2CYP3A4CYP2C9HIF1A | |
| SCHEMBL28254031 | 0.76 | CYP1A2 (0.38) | TDP1CYP1A2CYP3A4CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019334-A1 | STRENGTH ENHANCED PORTLAND CEMENT COMPOSITIONS | W.R. Grace & Co.-Conn. (US) | 2000-07-19 | — | — | EP | claimed |
| WO-1999016724-A1 | STRENGTH ENHANCED PORTLAND CEMENT COMPOSITIONS | W. R. GRACE & CO.-CONN. (US) | 1999-04-08 | — | — | WO | claimed |
| US-4681903-A | ESTERIFICATION, TRIS-ALKANOLAMINE OR TETRAKIS-ALKANOLDIAMINE, RIGIDITY, FOAMS | BAYER AKTIENGESELLSCHAFT (DE) | 1987-07-21 | — | — | US | disclosed |