SCHEMBL8209014

SCHEMBL8209014

CCCCCCCCCCCCCCCCNC(=O)CCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CASP2 P42575 1/20 1.00
NAAA Q02083 1/20 0.77
FAAH O00519 5/20 0.66
EPHX1 P07099 5/20 0.64
DNM1 Q05193 2/20 0.61
EPHX2 P34913 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3839655 1.00 CASP2 (1.00) CASP2NAAAFAAHEPHX1DNM1
SCHEMBL2497062 1.00 CASP2 (1.00) CASP2NAAAFAAHEPHX1DNM1
SCHEMBL12847246 1.00 CASP2 (1.00) CASP2NAAAFAAHEPHX1DNM1
SCHEMBL10149806 1.00 CASP2 (1.00) CASP2NAAAFAAHEPHX1DNM1
SCHEMBL9288380 1.00 CASP2 (1.00) CASP2NAAAFAAHEPHX1DNM1
SCHEMBL10149803 1.00 CASP2 (1.00) CASP2NAAAFAAHEPHX1DNM1
SCHEMBL12738558 1.00 CASP2 (1.00) CASP2NAAAFAAHEPHX1DNM1
SCHEMBL5065624 1.00 CASP2 (1.00) CASP2NAAAFAAHEPHX1DNM1
SCHEMBL12847247 1.00 CASP2 (1.00) CASP2NAAAFAAHEPHX1DNM1
SCHEMBL9795571 1.00 CASP2 (1.00) CASP2NAAAFAAHEPHX1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109562094-A Compositions and methods for enhancing antimicrobial agents 希拉匹克斯生物科学有限公司 2019-04-02 CN claimed
CN-107530317-A Combination of cannabinoids and N-acylethanolamines 希拉匹克斯生物科学有限公司 2018-01-02 CN claimed
CN-109562094-A Compositions and methods for enhancing antimicrobial agents 希拉匹克斯生物科学有限公司 2019-04-02 CN disclosed
CN-107613966-A Combination of opioids and N-acylethanolamines 希拉匹克斯生物科学有限公司 2018-01-19 CN disclosed
CN-107530317-A Combination of cannabinoids and N-acylethanolamines 希拉匹克斯生物科学有限公司 2018-01-02 CN disclosed
US-20160009657-A1 AMINE-CONTAINING LIPIDS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-01-14 US disclosed
US-9006487-B2 Amine-containing lipids and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2015-04-14 US disclosed
US-20120009222-A1 MODULATION OF THE IMMUNE RESPONSE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2012-01-12 US disclosed
US-20110052673-A1 THERAPEUTIC COMPOSITIONS SHIRE HUMAN GENETIC THERAPIES, INC. 2011-03-03 US disclosed
US-20110009641-A1 Amine-containing lipids and uses thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2011-01-13 US disclosed
WO-2010062322-A2 MODULATION OF THE IMMUNE RESPONSE MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2010-06-03 WO disclosed
US-6117562-A A THERMAL IMAGE TRANSFER INK LAYER FORMED ON THE SUPPORT; INK LAYER COMPRISING A COLORING AGENT, A RESIN AND A PLASTICIZER FOR LOWERING THE MELT VISCOSITY OF RESIN RICOH COMPANY, LTD. (JP) 2000-09-12 US disclosed
US-5716477-A CONSISTS OF A SUPPORT AND THERMAL IMAGE TRANSFER INK LAYER FORMED ON SAID SUPPORT CONSISTS OF A COLORING AGENT AND A PLASTICIZER FOR LOWERING MELT VISCOSITY OF THE RESIN, HIGH THERMOSENSITIVITY ON CLOTH, PLASTIC, OR PAPER RECEIVER RICOH COMPANY, LTD. (JP) 1998-02-10 US disclosed
US-4575734-A LEVCO DYES RICOH COMPANY, LTD. (JP) 1986-03-11 US disclosed
US-4562448-A Heat-sensitive transfer medium RICOH CO., LTD. (JP) 1985-12-31 US disclosed
US-4547788-A SHEET HAVING LAYER CONTAINING LEVCO DYE; ACCEPTOR SHEET CONTAININGCOLORING AGENT; POROUS FILLER RICOH COMPANY, LTD. (JP) 1985-10-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120009222-A1 MODULATION OF THE IMMUNE RESPONSE FCGRT, MYD88, C3AR1 CASP2 2840/4885NAAA 789/4885FAAH 858/4885
US-20110052673-A1 THERAPEUTIC COMPOSITIONS PHOSPHO1, SGMS1, APOB CASP2 1497/4885NAAA 625/4885FAAH 801/4885
US-20110009641-A1 Amine-containing lipids and uses thereof PHOSPHO1, CHMP4B, SGMS1 CASP2 3638/4885NAAA 78/4885FAAH 412/4885
US-20160009657-A1 AMINE-CONTAINING LIPIDS AND USES THEREOF PHOSPHO1, CHMP4B, SGMS1 CASP2 3638/4885NAAA 78/4885FAAH 412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.