Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.61 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 8/20 | 0.43 |
| ▸ | FNTB | P49356 | 8/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205622 | 0.93 | TAAR1 (0.62) | TAAR1NOTUMHDAC1HDAC6FNTA | |
| SCHEMBL8203976 | 0.85 | TAAR1 (0.64) | TAAR1NOTUMFNTAFNTB | |
| SCHEMBL8203733 | 0.82 | TAAR1 (0.59) | TAAR1HDAC1HDAC6FNTAFNTB | |
| SCHEMBL8203453 | 0.82 | TAAR1 (0.64) | TAAR1NOTUMFNTAFNTB | |
| SCHEMBL12993144 | 0.81 | TAAR1 (0.60) | TAAR1FNTAFNTB | |
| SCHEMBL12993166 | 0.78 | TAAR1 (0.58) | TAAR1FNTAFNTBHRH4 | |
| SCHEMBL1734486 | 0.78 | ADRA2A (0.44) | TAAR1NOTUMHDAC1HDAC6FNTA | |
| SCHEMBL508524 | 0.76 | TAAR1 (1.00) | TAAR1FNTAFNTB | |
| SCHEMBL11304976 | 0.76 | HTR6 (0.62) | NOTUMHDAC1HDAC6 | |
| SCHEMBL12993223 | 0.76 | TAAR1 (0.41) | TAAR1FNTAFNTBPKMCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008058867-A2 | SUBSTITUTED 4-IMIDAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-05-22 | — | — | WO | disclosed |