Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.68 |
| ▸ | MME | P08473 | 3/20 | 0.66 |
| ▸ | ACE | P12821 | 2/20 | 0.59 |
| ▸ | ECE1 | P42892 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6171453 | 1.00 | LTA4H (0.68) | LTA4HMMEACEECE1 | |
| SCHEMBL6173147 | 1.00 | LTA4H (0.68) | LTA4HMMEACEECE1 | |
| SCHEMBL6171450 | 1.00 | LTA4H (0.68) | LTA4HMMEACEECE1 | |
| SCHEMBL7367493 | 1.00 | LTA4H (0.68) | LTA4HMMEACEECE1 | |
| SCHEMBL6172199 | 0.89 | LTA4H (0.69) | LTA4HMMEACEECE1 | |
| SCHEMBL6172205 | 0.89 | LTA4H (0.69) | LTA4HMMEACEECE1 | |
| SCHEMBL10939531 | 0.85 | ITGB2 (0.62) | ACEECE1 | |
| SCHEMBL10947938 | 0.85 | ACE (0.60) | ACEECE1 | |
| SCHEMBL10944436 | 0.85 | ITGB2 (0.62) | ACEECE1 | |
| SCHEMBL10943428 | 0.85 | ACE (0.60) | ACEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136842-A | INHIBITION OF ENDOTHELIN-CONVERTING ENZYME | HOECHST MARION ROUSSEL (FR) | 2000-10-24 | — | — | US | disclosed |