Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638428 | 0.90 | POLB (0.55) | KMT2AMAPTTSHRHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL7641302 | 0.89 | POLB (0.54) | KMT2AMAPTTSHRHPGDALDH1A1 | |
| SCHEMBL7634529 | 0.85 | KEAP1 (0.48) | NAAAKMT2AKEAP1NFE2L2MAPT | |
| SCHEMBL7633791 | 0.85 | NAAA (0.50) | NAAATSHRHTTDRD2HPGD | |
| Hydrochloric Acid SCHEMBL7638047 | 0.84 | KEAP1 (0.47) | NAAAKMT2AKEAP1NFE2L2MAPT | |
| Hydrochloric Acid SCHEMBL7641092 | 0.84 | NAAA (0.49) | NAAATSHRHTTDRD2HPGD | |
| SCHEMBL7638117 | 0.82 | NAAA (0.54) | NAAATSHRHTTHPGDALDH1A1 | |
| SCHEMBL7632670 | 0.81 | NAAA (0.46) | NAAATSHRHTTDRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7641314 | 0.81 | NAAA (0.53) | NAAATSHRHTTHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL7632701 | 0.80 | NAAA (0.46) | NAAATSHRHTTDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114325-A | 1,2-di-substituted benzene-carboxamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2000-09-05 | — | — | US | disclosed |