Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8213958 | 0.77 | MMP8 (0.40) | MMP8MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL8200860 | 0.77 | HCAR2 (0.33) | MMP8TSHRALDH1A1HCAR2LMNA | |
| SCHEMBL8200865 | 0.77 | HCAR2 (0.33) | MMP8TSHRALDH1A1HCAR2LMNA | |
| SCHEMBL8200862 | 0.69 | HCAR2 (0.33) | HCAR2LTB4RLTB4R2 | |
| SCHEMBL10539056 | 0.67 | MMP8 (0.41) | MMP8MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL10538461 | 0.65 | HCAR2 (0.41) | KMT2AALDH1A1HCAR2CYP3A4LTB4R | |
| SCHEMBL10538467 | 0.65 | HCAR2 (0.41) | KMT2AALDH1A1HCAR2CYP3A4LTB4R | |
| SCHEMBL5172986 | 0.64 | ALDH1A1 (0.61) | KMT2ATSHRALDH1A1HSD17B10LMNA | |
| SCHEMBL1837098 | 0.64 | HCAR2 (0.51) | MMP8MEN1KMT2ATSHRNPC1 | |
| SCHEMBL16673423 | 0.63 | MMP8 (0.51) | MMP8MEN1KMT2ATSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021399-A2 | FUNGICIDES WITH HYDROXIMIC AND HYDRAZONIC GROUPS | AVENTIS CROPSCIENCE S.A. (FR) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998015512-A2 | FUNGICIDES WITH HYDROXIMIC AND HYDRAZONIC GROUPS | RHONE POULENC AGROCHIMIE (FR) | 1998-04-16 | — | — | WO | disclosed |