Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9395271 | 0.94 | TDP1 (0.53) | TDP1L3MBTL1ALDH1A1GAAHPGD | |
| SCHEMBL8189201 | 0.83 | TDP1 (0.66) | TDP1L3MBTL1ALDH1A1GAAHPGD | |
| SCHEMBL8191589 | 0.79 | MEN1 (0.50) | TDP1L3MBTL1ALDH1A1GAAHPGD | |
| SCHEMBL9395615 | 0.78 | TDP1 (0.47) | TDP1L3MBTL1ALDH1A1HPGDCYP3A4 | |
| SCHEMBL8178781 | 0.76 | TDP1 (0.62) | TDP1L3MBTL1CYP3A4CYP2C9CYP1A2 | |
| SCHEMBL8191568 | 0.76 | MEN1 (0.49) | TDP1L3MBTL1ALDH1A1GAAHPGD | |
| SCHEMBL8178771 | 0.74 | TDP1 (0.62) | TDP1L3MBTL1KMT2AMEN1HTT | |
| SCHEMBL28801777 | 0.71 | ALDH1A1 (0.64) | ALDH1A1GAAHPGDKMT2APOLB | |
| SCHEMBL15955998 | 0.71 | TDP1 (0.67) | TDP1L3MBTL1POLBGPR84HDAC8 | |
| SCHEMBL9395277 | 0.71 | TDP1 (0.49) | TDP1L3MBTL1ALDH1A1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127529-A | FORMS STABLE CHELATE COMPOUND USEFUL FOR LABELING BIOLOGICAL TARGETING COMPOUND RESIDUE | WALLAC OY (FI) | 2000-10-03 | — | — | US | disclosed |
| EP-0298939-B1 | Metal-chelating 2,6-disubstituted pyridine compounds and their use | WALLAC OY (FI) | 1994-01-12 | — | — | EP | disclosed |
| EP-0378652-A1 | OLIGONUCLEOTIDE HYBRIDIZATION PROBES AND MEANS FOR THE SYNTHESIS OF THE MOST PREFERRED PROBES | WALLAC OY (FI) | 1990-07-25 | — | — | EP | disclosed |
| WO-1990000622-A1 | OLIGONUCLEOTIDE HYBRIDIZATION PROBES AND MEANS FOR THE SYNTHESIS OF THE MOST PREFERRED PROBES | WALLAC OY (FI) | 1990-01-25 | — | — | WO | disclosed |
| EP-0298939-A1 | Metal-chelating 2,6-disubstituted pyridine compounds and their use | WALLAC OY (FI) | 1989-01-11 | — | — | EP | disclosed |