Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 18/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 16/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 12/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8209766 | 1.00 | OPRM1 (0.60) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8208003 | 0.90 | OPRD1 (0.69) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8208000 | 0.90 | OPRD1 (0.69) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8207577 | 0.88 | OPRM1 (0.59) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8199155 | 0.86 | OPRM1 (0.58) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8199153 | 0.86 | OPRM1 (0.58) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8206821 | 0.86 | OPRM1 (0.66) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8206819 | 0.86 | OPRM1 (0.66) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8208118 | 0.86 | OPRM1 (0.65) | OPRM1OPRK1OPRD1 | |
| SCHEMBL8208119 | 0.86 | OPRM1 (0.65) | OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150524-A | MORPHINAN DERIVATIVES | CENES LTD. (GB) | 2000-11-21 | — | — | US | disclosed |