Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | MARS1 | P56192 | 8/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.34 |
| ▸ | BHMT | Q93088 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16169040 | 0.80 | FAAH (0.37) | RNPEPFAAHMETAP2METAP1CYP2C9 | |
| SCHEMBL753367 | 0.79 | SLC1A2 (0.37) | FAAHMETAP1DPP4DPP9 | |
| SCHEMBL9045357 | 0.76 | DPP7 (0.43) | METAP1DPP4DPP9 | |
| SCHEMBL6500352 | 0.76 | DPP7 (0.43) | METAP1DPP4DPP9 | |
| SCHEMBL28489178 | 0.76 | RNPEP (0.39) | RNPEPMARS1ANPEPENPEPBHMT | |
| SCHEMBL19486242 | 0.75 | FAAH (0.38) | FAAHDPP4DPP9 | |
| SCHEMBL28837332 | 0.75 | FAAH (0.38) | FAAHDPP4DPP9 | |
| SCHEMBL6628997 | 0.75 | FAAH (0.38) | FAAHDPP4DPP9 | |
| SCHEMBL6629003 | 0.75 | FAAH (0.38) | FAAHDPP4DPP9 | |
| SCHEMBL26092201 | 0.74 | RNPEP (0.38) | RNPEPMARS1ANPEPENPEPBHMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054865-A1 | FARNESYL TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999041235-A1 | FARNESYL TRANSFERASE INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-08-19 | — | — | WO | disclosed |