Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 3/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045357 | 0.89 | DPP7 (0.43) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL6500352 | 0.89 | DPP7 (0.43) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL6628997 | 0.83 | FAAH (0.38) | SLC1A2SLC1A1SLC1A3FAAHDPP4 | |
| SCHEMBL6629003 | 0.83 | FAAH (0.38) | SLC1A2SLC1A1SLC1A3FAAHDPP4 | |
| SCHEMBL8209839 | 0.79 | RNPEP (0.36) | FAAHDPP4DPP9METAP1 | |
| SCHEMBL28837332 | 0.79 | FAAH (0.38) | SLC1A1FAAHDPP4DPP9 | |
| SCHEMBL19486242 | 0.79 | FAAH (0.38) | SLC1A1FAAHDPP4DPP9 | |
| SCHEMBL11342489 | 0.79 | SLC1A2 (0.42) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL8207593 | 0.79 | SLC1A2 (0.42) | SLC1A2SLC1A1SLC1A3GRIK1GRIK2 | |
| SCHEMBL25782046 | 0.78 | FAAH (0.37) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |