Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 9/20 | 0.52 |
| ▸ | MMP9 | P14780 | 6/20 | 0.52 |
| ▸ | MMP1 | P03956 | 11/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.50 |
| ▸ | MMP2 | P08253 | 4/20 | 0.45 |
| ▸ | MMP3 | P08254 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934669 | 0.85 | MMP13 (0.53) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL6930642 | 0.84 | MMP13 (0.59) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL6932436 | 0.82 | MMP13 (0.70) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL6933169 | 0.82 | MMP13 (0.54) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL6932952 | 0.81 | MMP13 (0.51) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL7001320 | 0.81 | MMP1 (0.55) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL6933449 | 0.80 | MMP13 (0.72) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL6933028 | 0.80 | MMP13 (0.72) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL6928553 | 0.80 | MMP13 (0.72) | MMP13MMP9MMP1ADAM17MMP2 | |
| SCHEMBL5157759 | 0.77 | MMP1 (0.51) | MMP13MMP9MMP1ADAM17MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973512-A1 | N-HYDROXY-2-(ALKYL, ARYL OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS | American Cyanamid Company (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998037877-A1 | N-HYDROXY-2-(ALKYL, ARYL OR HETEROARYL SULFANYL, SULFINYL OR SULFONYL)-3-SUBSTITUTED ALKYL, ARYL OR HETEROARYLAMIDES AS MATRIX METALLOPROTEINASE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1998-09-03 | — | — | WO | disclosed |