Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 13/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210253 | 0.67 | CACNA1H (0.51) | CACNA1HGAA | |
| SCHEMBL12876210 | 0.64 | CACNA1H (1.00) | CACNA1H | |
| SCHEMBL8210538 | 0.64 | CACNA1H (0.63) | CACNA1H | |
| SCHEMBL5799771 | 0.60 | PKM (0.50) | GAAPOLBGFER | |
| SCHEMBL12904902 | 0.55 | TAS1R3 (0.47) | POLBTAS1R3TAS1R1 | |
| SCHEMBL3241409 | 0.54 | TAS1R3 (0.46) | CYP2C9POLBTAS1R3TAS1R1 | |
| SCHEMBL711890 | 0.54 | TAS1R3 (0.46) | CYP2C9POLBTAS1R3TAS1R1 | |
| SCHEMBL28648395 | 0.53 | L3MBTL1 (0.49) | CYP2C9POLBTAS1R3TAS1R1 | |
| SCHEMBL10218991 | 0.53 | TAS1R3 (0.49) | CYP2C9POLBTAS1R3TAS1R1 | |
| SCHEMBL10218987 | 0.53 | TAS1R3 (0.49) | CYP2C9POLBTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033464-A2 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF DISORDERS OF THE LIPID METABOLISM | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |