Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13892308 | 0.82 | RAB9A (0.45) | IDO1IDO2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15238147 | 0.80 | NPC1 (0.44) | RAB9ANPC1NFKB1NFKB2RELA | |
| Hydrochloric Acid SCHEMBL5855080 | 0.78 | NPC1 (0.43) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL5504840 | 0.76 | NPC1 (0.41) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL13299076 | 0.72 | MAPK8 (0.43) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL30747866 | 0.72 | IDO1 (0.56) | IDO1IDO2SMN1; SMN2NR1H2NR1H3 | |
| SCHEMBL13846109 | 0.72 | PDK2 (0.48) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL2647877 | 0.70 | PDK2 (0.50) | IDO1SMN1; SMN2PDK2TSHRUSP2 | |
| SCHEMBL344042 | 0.69 | RAB9A (0.53) | RAB9ANPC1NFKB1NFKB2RELA | |
| SCHEMBL22053088 | 0.69 | TYK2 (0.41) | RAB9ANPC1NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021733-A2 | TETRAZOLYL ACYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |