Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Betaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4048487 | 0.91 | TSHR (0.34) | TSHR | |
| Water SCHEMBL462687 | 0.90 | TSHR (0.33) | TSHR | |
| SCHEMBL23794910 | 0.87 | TSHR (0.33) | TSHR | |
| Betaine SCHEMBL3693558 | 0.83 | TSHR (0.33) | TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL135768 | 0.83 | TSHR (0.34) | TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL907529 | 0.83 | TSHR (0.34) | TSHRALDH1A1LMNAAPEX1 | |
| SCHEMBL23794907 | 0.83 | TSHR (0.36) | TSHRALDH1A1 | |
| Betaine SCHEMBL3113299 | 0.81 | TSHR (0.45) | TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL10908499 | 0.79 | TSHR (0.37) | TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL17603223 | 0.77 | TSHR (0.30) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074116-A1 | FABRICATION AND MODIFICATION OF POLYMER MEMBRANES USING INK-JET PRINTING | B.G. Negev Technologies and Applications Ltd. (IL) | 2016-10-05 | — | — | EP | claimed |
| US-20160263530-A1 | FABRICATION AND MODIFICATION OF POLYMER MEMBRANES USING INK-JET PRINTING | B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD (IL) | 2016-09-15 | — | — | US | claimed |
| US-9196405-B2 | Stable iron oxide nanoparticles and method of production | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2015-11-24 | — | — | US | claimed |
| US-9056125-B2 | Films for controlled cell growth and adhesion | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2015-06-16 | — | — | US | claimed |
| WO-2015079442-A1 | FABRICATION AND MODIFICATION OF POLYMER MEMBRANES USING INK-JET PRINTING | B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD (IL) | 2015-06-04 | — | — | WO | claimed |
| US-20130256583-A1 | Stable Iron Oxide Nanoparticles and Method of Production | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2013-10-03 | — | — | US | claimed |
| US-7618693-B2 | Containing zwitterion copolymer; colorfastness, photostability | CIBA SPECIALTY CHEMICALS CORP. (US) | 2009-11-17 | — | — | US | claimed |
| US-20090202816-A1 | STABILIZED SILICA COLLOID | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-08-13 | — | — | US | claimed |
| US-7544402-B2 | Containing zwitterion copiolymer; colorfastness, photostability | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-06-09 | — | — | US | claimed |
| US-7544401-B2 | Ink jet recording medium | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-06-09 | — | — | US | claimed |
| US-6709551-B2 | FOR PAPERMAKING; ADJUSTMENT OF CONFINING, DRAINAGE OF FIBROUS SUSPENSION | ONDEO NALCO COMPANY | 2004-03-23 | — | — | US | claimed |
| US-20030155091-A1 | High molecular weight cationic and anionic polymers comprising zwitterionic monomers | ECOLAB USA INC. | 2003-08-21 | — | — | US | claimed |
| US-6590051-B1 | Polyampholytes used to increase retention and drainage in fiber suspensions or pulps used in papermaking; clarification | ONDEO NALCO COMPANY | 2003-07-08 | — | — | US | claimed |
| US-20030116317-A1 | Composition and method for recovering hydrocarbon fluids from a subterranean reservoir | HARBISON-FISCHER, INC. | 2003-06-26 | — | — | US | claimed |
| WO-2003037641-A2 | INK JET RECORDING MEDIUM | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-08 | — | — | WO | claimed |
| JP-2003504476-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1198503-A1 | HIGH MOLECULAR WEIGHT ZWITTERIONIC POLYMERS | NALCO CHEMICAL COMPANY (US) | 2002-04-24 | — | — | EP | claimed |
| US-6335005-B1 | Aqueous cosmetic compounds | BASF AKTIENGESELLSCHAFT (DE) | 2002-01-01 | — | — | US | claimed |
| US-6313246-B1 | UNSATURATED QUATERNARY AMMONIUM OR SULFONIUM SALT AND NONIONIC MONOMERS ; WATER IN OIL EMULSION, DISPERSION OR GEL; PAPERMAKING | NALCO CHEMICAL COMPANY | 2001-11-06 | — | — | US | claimed |
| WO-2001004201-A1 | HIGH MOLECULAR WEIGHT ZWITTERIONIC POLYMERS | NALCO CHEMICAL COMPANY (US) | 2001-01-18 | — | — | WO | claimed |