Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Betaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3887838 | 0.91 | TSHR (0.34) | TSHR | |
| Water SCHEMBL15530721 | 0.90 | TSHR (0.33) | TSHR | |
| SCHEMBL23794906 | 0.87 | TSHR (0.33) | TSHR | |
| Betaine SCHEMBL821050 | 0.83 | TSHR (0.34) | TSHRALDH1A1LMNAAPEX1 | |
| SCHEMBL23794912 | 0.83 | TSHR (0.36) | TSHR | |
| Betaine SCHEMBL907529 | 0.78 | TSHR (0.34) | TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL3895955 | 0.77 | TSHR (0.38) | TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL5167715 | 0.77 | TSHR (0.41) | TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL3693558 | 0.76 | TSHR (0.33) | TSHRALDH1A1LMNAAPEX1 | |
| Betaine SCHEMBL5170190 | 0.76 | TSHR (0.43) | TSHRALDH1A1LMNAAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 385 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11008538-B2 | Reduced misting alkaline and neutral cleaning, sanitizing, and disinfecting compositions via the use of high molecular weight water-in-oil emulsion polymers | ECOLAB USA INC. (US) | 2021-05-18 | — | — | US | claimed |
| US-20210079143-A1 | STRENGTHENING RESINS AND PROCESSES FOR MAKING AND USING SAME | ECOLAB USA INC. (US) | 2021-03-18 | — | — | US | claimed |
| US-20190330573-A1 | REDUCED MISTING ALKALINE AND NEUTRAL CLEANING, SANITIZING, AND DISINFECTING COMPOSTIONS VIA THE USE OF HIGH MOLECULAR WEIGHT WATER-IN-OIL EMULSION POLYMERS | ECOLAB USA INC. | 2019-10-31 | — | — | US | claimed |
| US-10392587-B2 | Reduced misting alkaline and neutral cleaning, sanitizing, and disinfecting compositions via the use of high molecular weight water-in-oil emulsion polymers | ECOLAB USA INC. (US) | 2019-08-27 | — | — | US | claimed |
| US-10370626-B2 | Reduced misting acidic cleaning, sanitizing, and disinfecting compositions via the use of high molecular weight water-in-oil emulsion polymers | ECOLAB USA INC. (US) | 2019-08-06 | — | — | US | claimed |
| EP-3464541-A1 | REDUCED MISTING ALKALINE AND NEUTRAL CLEANING, SANITIZING, AND DISINFECTING COMPOSITIONS VIA THE USE OF HIGH MOLECULAR WEIGHT WATER-IN-OIL EMULSION POLYMERS | Ecolab USA Inc. (US) | 2019-04-10 | — | — | EP | claimed |
| US-10087082-B2 | Stabilized silica colloid | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2018-10-02 | — | — | US | claimed |
| US-20180099072-A1 | INJECTABLE TISSUE SUPPLEMENT | TRUSTEES OF BOSTON UNIVERSITY (US) | 2018-04-12 | — | — | US | claimed |
| WO-2017205334-A1 | REDUCED MISTING ALKALINE AND NEUTRAL CLEANING, SANITIZING, AND DISINFECTING COMPOSITIONS VIA THE USE OF HIGH MOLECULAR WEIGHT WATER-IN-OIL EMULSION POLYMERS | ECOLAB USA INC. (US) | 2017-11-30 | — | — | WO | claimed |
| US-20170335253-A1 | REDUCED MISTING ALKALINE AND NEUTRAL CLEANING, SANITIZING, AND DISINFECTING COMPOSTIONS VIA THE USE OF HIGH MOLECULAR WEIGHT WATER-IN-OIL EMULSION POLYMERS | ECOLAB USA INC. | 2017-11-23 | — | — | US | claimed |
| US-6709551-B2 | FOR PAPERMAKING; ADJUSTMENT OF CONFINING, DRAINAGE OF FIBROUS SUSPENSION | ONDEO NALCO COMPANY | 2004-03-23 | — | — | US | claimed |
| US-20030155091-A1 | High molecular weight cationic and anionic polymers comprising zwitterionic monomers | ECOLAB USA INC. | 2003-08-21 | — | — | US | claimed |
| US-6590051-B1 | Polyampholytes used to increase retention and drainage in fiber suspensions or pulps used in papermaking; clarification | ONDEO NALCO COMPANY | 2003-07-08 | — | — | US | claimed |
| WO-2003054030-A2 | POLY(VINYLALCOHOL)-CO-POLY(VINYLAMINE) POLYMERS COMPRISING FUNCTIOAL MOIETIES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-07-03 | — | — | WO | claimed |
| WO-2003037641-A2 | INK JET RECORDING MEDIUM | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-08 | — | — | WO | claimed |
| JP-2003504476-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1198503-A1 | HIGH MOLECULAR WEIGHT ZWITTERIONIC POLYMERS | NALCO CHEMICAL COMPANY (US) | 2002-04-24 | — | — | EP | claimed |
| US-6313246-B1 | UNSATURATED QUATERNARY AMMONIUM OR SULFONIUM SALT AND NONIONIC MONOMERS ; WATER IN OIL EMULSION, DISPERSION OR GEL; PAPERMAKING | NALCO CHEMICAL COMPANY | 2001-11-06 | — | — | US | claimed |
| WO-2001004201-A1 | HIGH MOLECULAR WEIGHT ZWITTERIONIC POLYMERS | NALCO CHEMICAL COMPANY (US) | 2001-01-18 | — | — | WO | claimed |
| US-5512277-A | APPLYING CATIONIC POLYMER HAVING SALT FORMING GROUP TO SKIN, PEELING OFF AFTER DRYING | KAO CORPORATION (JP) | 1996-04-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180099072-A1 | INJECTABLE TISSUE SUPPLEMENT | MMP1, COL1A1, MYOC | TSHR 621/4885ALDH1A1 255/4885LMNA 2439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.