Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4048487 | 0.99 | TSHR (0.34) | TSHR | |
| SCHEMBL23794910 | 0.94 | TSHR (0.33) | TSHR | |
| Betaine SCHEMBL821050 | 0.90 | TSHR (0.34) | TSHR | |
| SCHEMBL23794907 | 0.90 | TSHR (0.36) | TSHR | |
| Water SCHEMBL7896363 | 0.83 | THRB (0.37) | TSHR | |
| SCHEMBL13749923 | 0.80 | TSHR (0.42) | TSHR | |
| Water SCHEMBL15530721 | 0.80 | TSHR (0.33) | TSHR | |
| Water SCHEMBL28053922 | 0.80 | TSHR (0.31) | TSHR | |
| Hydrochloric Acid SCHEMBL28570820 | 0.79 | TSHR (0.45) | TSHR | |
| Bromide SCHEMBL28356825 | 0.79 | TSHR (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113293508-A | Composite fiber membrane and preparation method and application thereof | 内蒙古工业大学 | 2021-08-24 | — | — | CN | claimed |
| US-20150109573-A1 | SURFACE COATINGS FOR BIOLOGICAL IMPLANTS AND PROSTHESES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION | 2015-04-23 | — | — | US | claimed |
| WO-2013166358-A1 | SURFACE COATINGS FOR BIOLOGICAL IMPLANTS AND PROSTHESES | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2013-11-07 | — | — | WO | claimed |
| WO-2023044463-A1 | SILK FIBROIN DERIVED BRUSH-LIKE POLYMERS | UNIVERSITY OF CONNECTICUT (US) | 2023-03-23 | — | — | WO | disclosed |
| US-20230062833-A1 | DRYER, DRYING METHOD, AND DEHUMIDIFICATION FILTER | PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) | 2023-03-02 | — | — | US | disclosed |
| CN-113293508-A | Composite fiber membrane and preparation method and application thereof | 内蒙古工业大学 | 2021-08-24 | — | — | CN | disclosed |
| CN-113293508-A | Composite fiber membrane and preparation method and application thereof | 内蒙古工业大学 | 2021-08-24 | — | — | CN | disclosed |
| US-9550011-B2 | Surface coatings for biological implants and prostheses | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2017-01-24 | — | — | US | disclosed |
| US-20150109573-A1 | SURFACE COATINGS FOR BIOLOGICAL IMPLANTS AND PROSTHESES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION | 2015-04-23 | — | — | US | disclosed |
| WO-2013166358-A1 | SURFACE COATINGS FOR BIOLOGICAL IMPLANTS AND PROSTHESES | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2013-11-07 | — | — | WO | disclosed |
| EP-2440977-A1 | NEGATIVE-WORKING IMAGEABLE ELEMENTS | Eastman Kodak Company (US) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010144119-A1 | NEGATIVE-WORKING IMAGEABLE ELEMENTS | EASTMAN KODAK COMPANY (US) | 2010-12-16 | — | — | WO | disclosed |
| US-7074867-B2 | From a sulfonate compound containing unsaturated ester group; membrane | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2006-07-11 | — | — | US | disclosed |
| US-20040171781-A1 | Ion conducting polymers | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2004-09-02 | — | — | US | disclosed |
| US-20030045664-A1 | High ion conductive polymers, methods of producing, membrane formed therefrom and related compounds | INSTITUTE OF MATERIALS RESEARCH AND ENGINEERING (SG) | 2003-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171781-A1 | Ion conducting polymers | CACNA1E, VDAC1, HVCN1 | TSHR 3664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.