Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.73 |
| ▸ | DPP4 | P27487 | 16/20 | 0.69 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.68 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12292348 | 1.00 | DPP7 (0.73) | DPP7DPP4DPP8DPP9KCNH2 | |
| SCHEMBL8350273 | 0.82 | DPP7 (0.71) | DPP7DPP4DPP8DPP9KCNH2 | |
| SCHEMBL16519522 | 0.81 | DPP4 (0.58) | DPP7DPP4DPP8DPP9KCNH2 | |
| SCHEMBL13882614 | 0.81 | DPP7 (1.00) | DPP7DPP4DPP8DPP9 | |
| SCHEMBL10074327 | 0.81 | DPP7 (1.00) | DPP7DPP4DPP8DPP9 | |
| SCHEMBL7289506 | 0.78 | DPP7 (0.61) | DPP7DPP4DPP8DPP9KCNH2 | |
| SCHEMBL7289498 | 0.78 | DPP7 (0.61) | DPP7DPP4DPP8DPP9KCNH2 | |
| SCHEMBL13852672 | 0.78 | DPP7 (0.66) | DPP7DPP4DPP8DPP9KCNH2 | |
| SCHEMBL27869019 | 0.78 | DPP7 (0.60) | DPP7DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL6766509 | 0.77 | DPP7 (0.59) | DPP7DPP4DPP8DPP9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140287040-A1 | Formulation | NOVARTIS AG (CH) | 2014-09-25 | — | — | US | disclosed |
| WO-2008028914-A1 | COMBINATION TREATMENT FOR DIABETES MELLITUS | NYCOMED GMBH (DE) | 2008-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140287040-A1 | Formulation | DPP4, DPP3, DPP7 | DPP7 3/4885DPP4 1/4885DPP8 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.