SCHEMBL10074327

SCHEMBL10074327

NCCCCC(N)C(=O)N1CCSC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 13/20 1.00
DPP4 P27487 10/20 1.00
DPP8 Q6V1X1 7/20 1.00
DPP9 Q86TI2 6/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13882614 1.00 DPP7 (1.00) DPP7DPP4DPP8DPP9
SCHEMBL12292348 0.81 DPP7 (0.73) DPP7DPP4DPP8DPP9
SCHEMBL8210690 0.81 DPP7 (0.73) DPP7DPP4DPP8DPP9
SCHEMBL10078391 0.80 DPP4 (0.66) DPP7DPP4DPP8DPP9
SCHEMBL8350273 0.79 DPP7 (0.71) DPP7DPP4DPP8DPP9
SCHEMBL7301538 0.78 DPP4 (0.64) DPP7DPP4DPP8DPP9
SCHEMBL7301534 0.78 DPP4 (0.64) DPP7DPP4DPP8DPP9
SCHEMBL2694035 0.78 DPP7 (0.64) DPP7DPP4DPP8DPP9
SCHEMBL29049118 0.78 DPP7 (0.64) DPP7DPP4DPP8DPP9
SCHEMBL1070608 0.78 DPP7 (0.81) DPP7DPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2418196-A1 Dual alanyl-aminopeptidase and dipeptidyl-peptidase IV inhibitors IMTM GmbH (DE) 2012-02-15 EP disclosed