SCHEMBL27869019

SCHEMBL27869019

CCCCCCC(N)C(=O)N1CCSCC1

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 12/20 0.60
DPP4 P27487 10/20 0.60
DPP8 Q6V1X1 6/20 0.60
DPP9 Q86TI2 5/20 0.60
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
FAP Q12884 1/20 0.42
GRIK1 P39086 1/20 0.41
GRIK2 Q13002 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12352122 0.83 DPP7 (0.49) DPP7DPP4DPP8DPP9GNAI3
SCHEMBL30612344 0.82 L3MBTL1 (0.51) DPP7DPP4DPP8DPP9FAP
SCHEMBL12352134 0.79 HTT (0.46) DPP7DPP4DPP8DPP9FAP
SCHEMBL12352124 0.79 DPP4 (0.47) DPP7DPP4DPP8DPP9GNAI3
SCHEMBL1070608 0.78 DPP7 (0.81) DPP7DPP4DPP8DPP9FAP
SCHEMBL23049269 0.78 DPP7 (0.46) DPP7DPP4DPP8DPP9GNAI3
SCHEMBL12352130 0.78 DPP7 (0.46) DPP7DPP4DPP8DPP9GNAI3
SCHEMBL12352128 0.78 DPP7 (0.64) DPP7DPP4DPP8DPP9GNAI3
SCHEMBL8210690 0.78 DPP7 (0.73) DPP7DPP4DPP8DPP9
SCHEMBL12292348 0.78 DPP7 (0.73) DPP7DPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102453001-A Thiomorpholine compound and preparation method and application thereof INST MATERIA MEDICA CAMS 2012-05-16 CN claimed
CN-102453001-A Thiomorpholine compound and preparation method and application thereof INST MATERIA MEDICA CAMS 2012-05-16 CN disclosed