SCHEMBL8210873

SCHEMBL8210873

C[C@@H](O)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OC(C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CASP3 P42574 4/20 0.48
▸ KMT2A Q03164 1/20 0.47
▸ PIN1 Q13526 1/20 0.45
▸ MDM4 O15151 1/20 0.45
▸ TP53 P04637 1/20 0.45
▸ EPHX2 P34913 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28522099 1.00 CASP3 (0.48) CASP3KMT2APIN1MDM4TP53
SCHEMBL31512913 0.89 CASP3 (0.47) CASP3KMT2APIN1MDM4TP53
SCHEMBL31098370 0.89 CASP3 (0.47) CASP3KMT2APIN1MDM4TP53
SCHEMBL29403817 0.88 CASP3 (0.45) CASP3KMT2APIN1MDM4TP53
SCHEMBL21403411 0.88 CASP3 (0.45) CASP3KMT2APIN1MDM4TP53
SCHEMBL21432488 0.88 CASP3 (0.45) CASP3KMT2APIN1MDM4TP53
SCHEMBL21416088 0.88 CASP3 (0.45) CASP3KMT2APIN1MDM4TP53
SCHEMBL21403410 0.88 CASP3 (0.45) CASP3KMT2APIN1MDM4TP53
SCHEMBL31098371 0.88 CASP3 (0.45) CASP3KMT2APIN1MDM4TP53
SCHEMBL7390390 0.88 CASP3 (0.52) CASP3KMT2APIN1MDM4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119591674-A Cyclohexapeptide and preparation method and application thereof 陕西未来多肽生物科技有限公司 2025-03-11 — — CN claimed
CN-115232195-A Oligopeptide two-dimensional nanomaterial and application thereof 忻州师范学院 2022-10-25 — — CN claimed
CN-114948860-A Supermolecule hydrogel nano material, gelator, preparation method and application thereof 东南大学 2022-08-30 — — CN claimed
CN-102702343-A Method for synthesizing tesamorelin through solid phases GL BIOCHEM SHANGHAI CO LTD 2012-10-03 — — CN claimed
EP-0981556-A1 ETHYLENE/ALPHA-OLEFIN/DIENE INTERPOLYMERS AND THEIR PREPARATION THE DOW CHEMICAL COMPANY (US) 2000-03-01 — — EP claimed
WO-1998049212-A1 ETHYLENE/ALPHA-OLEFIN/DIENE INTERPOLYMERS AND THEIR PREPARATION THE DOW CHEMICAL COMPANY (US) 1998-11-05 — — WO claimed
CN-120192365-A Colipase inhibiting peptide and application thereof 宜客美股份有限公司 2025-06-24 — — CN disclosed
CN-120136974-A Cyclopentapeptide-4, preparation method thereof and polypeptide cosmetic 陕西未来多肽生物科技有限公司 2025-06-13 — — CN disclosed
CN-119591674-A Cyclohexapeptide and preparation method and application thereof 陕西未来多肽生物科技有限公司 2025-03-11 — — CN disclosed
CN-118356515-A FAP-targeted conjugate with radionuclide and application thereof 广州医科大学附属第一医院(广州呼吸中心) 2024-07-19 — — CN disclosed
US-12012468-B2 Cyclic polypeptides for PCSK9 inhibition MERCK SHARP & DOHME LLC (US) 2024-06-18 — — US disclosed
CN-117720621-B Alpha-amylase inhibiting peptide and application thereof 北京晶泰科技有限公司 2024-05-31 — — CN disclosed
CN-118047737-A Preparation method of amide compound 湖北师范大学 2024-05-17 — — CN disclosed
EP-3345917-A1 ANTIPROTOZOAL COMPOUNDS Bacoba AG (CH) 2018-07-11 — — EP disclosed
US-9605020-B2 Method for producing dipeptide derivative containing disubstituted amino acid residue NAGASE & CO., LTD. (JP) 2017-03-28 — — US disclosed
US-20160362445-A1 SOLID PHASE PEPTIDE SYNTHESIS VIA SIDE CHAIN ATTACHMENT CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2016-12-15 — — US disclosed
US-20160207958-A1 METHOD FOR PRODUCING DIPEPTIDE DERIVATIVE CONTAINING DISUBSTITUTED AMINO ACID RESIDUE NAGASE & CO., LTD. (JP) 2016-07-21 — — US disclosed
US-9388212-B2 Solid phase peptide synthesis via side chain attachment CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2016-07-12 — — US disclosed
US-20140235789-A1 SOLID PHASE PEPTIDE SYNTHESIS VIA SIDE CHAIN ATTACHMENT CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2014-08-21 — — US disclosed
CN-102702343-A Method for synthesizing tesamorelin through solid phases GL BIOCHEM SHANGHAI CO LTD 2012-10-03 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160362445-A1 SOLID PHASE PEPTIDE SYNTHESIS VIA SIDE CHAIN ATTACHMENT HDGF, VIP, HDGFL3 CASP3 4643/4885KMT2A 2268/4885PIN1 1757/4885
US-20140235789-A1 SOLID PHASE PEPTIDE SYNTHESIS VIA SIDE CHAIN ATTACHMENT HDGF, VIP, HDGFL3 CASP3 4643/4885KMT2A 2268/4885PIN1 1757/4885
US-12012468-B2 Cyclic polypeptides for PCSK9 inhibition PCSK9, LDLR, PCSK7 CASP3 2160/4885KMT2A 4061/4885PIN1 1290/4885
US-20160207958-A1 METHOD FOR PRODUCING DIPEPTIDE DERIVATIVE CONTAINING DISUBSTITUTED AMINO ACID RESIDUE DNPEP, PEPD, ASNS CASP3 3125/4885KMT2A 2329/4885PIN1 868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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