⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1700958 | 0.74 | CHRNB2 (0.48) | — | |
| SCHEMBL1577795 | 0.74 | CHRNB2 (0.48) | — | |
| SCHEMBL1577796 | 0.74 | CHRNB2 (0.48) | — | |
| SCHEMBL6036521 | 0.73 | — | — | |
| SCHEMBL103027 | 0.73 | — | — | |
| SCHEMBL5941027 | 0.73 | — | — | |
| SCHEMBL103026 | 0.73 | — | — | |
| SCHEMBL8589134 | 0.71 | — | — | |
| SCHEMBL398065 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL28565695 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 782 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507227-B | Benzisothiazole compound, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-06-21 | — | — | CN | claimed |
| US-20230303584-A1 | 4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE SUMO INHIBITORS AND USES THEREOF | CIT THERAPEUTICS LLC | 2023-09-28 | — | — | US | claimed |
| CN-115504973-A | Benzisoxazole compound, preparation method thereof, pharmaceutical composition and application | 中国医学科学院药物研究所 | 2022-12-23 | — | — | CN | claimed |
| CN-115466251-A | Fused heterocyclic compound, preparation method thereof, pharmaceutical composition and application | 中国医学科学院药物研究所 | 2022-12-13 | — | — | CN | claimed |
| CN-114591318-A | Pyrazolo heterocyclic compound, preparation method thereof, pharmaceutical composition and application | 中国医学科学院药物研究所 | 2022-06-07 | — | — | CN | claimed |
| CN-114507227-A | Benzisothiazole compound, preparation method thereof, pharmaceutical composition and application | 中国医学科学院药物研究所 | 2022-05-17 | — | — | CN | claimed |
| CN-114507243-A | Isothiazole heterocyclic compound, preparation method thereof, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-05-17 | — | — | CN | claimed |
| US-20220135557-A1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-05-05 | — | — | US | claimed |
| CN-109456324-B | Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-04-22 | — | — | CN | claimed |
| EP-3891149-A1 | RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2021-10-13 | — | — | EP | claimed |
| EP-0517052-A1 | Substituted imidazolinyl-pyrimidines | BAYER AG (DE) | 1992-12-09 | — | — | EP | claimed |
| EP-0220066-B1 | CARBOXAMIDE DERIVATIVES | ICI AMERICAS INC. (US) | 1992-03-25 | — | — | EP | claimed |
| WO-1992001677-A1 | PYRIMIDINYL AND TRIAZINYL HERBICIDES | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-02-06 | — | — | WO | claimed |
| US-5049679-A | Leukotriene antagonists | ICI AMERICAS INC. (US) | 1991-09-17 | — | — | US | claimed |
| US-4918094-A | Carboxamide derivatives of indoles and leucotriene antagonizing use thereof | ICI AMERICAS INC. (US) | 1990-04-17 | — | — | US | claimed |
| US-4837235-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ICI AMERICAS INC. (US) | 1989-06-06 | — | — | US | claimed |
| EP-0227241-A2 | Medicinal indole and indazole keto sulphone derivatives | ZENECA INC. (US) | 1987-07-01 | — | — | EP | claimed |
| EP-0220066-A2 | Carboxamide derivatives | ICI AMERICAS INC. (US) | 1987-04-29 | — | — | EP | claimed |
| EP-0077963-A1 | 2-Nitro-5-(4-trifluoromethyl-phenoxy)-benzyl derivatives, process for their preparation, and their use as herbicides and plant growth regulators | BAYER AG (DE) | 1983-05-04 | — | — | EP | claimed |
| US-4267319-A | CATIONIC DYES AND N-HETEROCYCLIC CATIONIC POLYMERS; PRINTING PAPER; ORANGE OR RED | BASF AKTIENGESELLSCHAFT (DE) | 1981-05-12 | — | — | US | claimed |