SCHEMBL1700958

SCHEMBL1700958

CN(C)C(=O)/C=C\C(=O)N(C)C

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.48
CHRNB4 P30926 1/20 0.48
CHRNA3 P32297 1/20 0.48
CHRNA4 P43681 1/20 0.48
ALDH1A1 P00352 2/20 0.41
TSHR P16473 2/20 0.41
NFKB1 P19838 1/20 0.37
THPO P40225 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPT P10636 1/20 0.37
APEX1 P27695 1/20 0.37
PMP22 Q01453 1/20 0.37
TDP1 Q9NUW8 1/20 0.32
NR4A2 P43354 1/20 0.32
KEAP1 Q14145 1/20 0.30
NFE2L2 Q16236 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1577796 1.00 CHRNB2 (0.48) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL1577795 1.00 CHRNB2 (0.48) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL4162860 0.87 TSHR (0.53) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL30899333 0.87 CHRNB2 (0.41) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL5176807 0.87 TSHR (0.53) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL4162857 0.87 TSHR (0.53) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL13768857 0.87 CHRNB2 (0.41) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL5176271 0.85 CHRNB2 (0.40) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL1029179 0.85 CHRNB2 (0.40) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
SCHEMBL4779558 0.85 CHRNB2 (0.40) CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0790335-B1 Cut-resistant aramid fibres, yarns containing these fibres and their use UNIV CLEMSON RES FOUNDATION (US) 2005-06-15 EP claimed
US-4389521-A AROMATIC POLYAMIDE TEIJIN LIMITED (JP) 1983-06-21 US claimed
EP-3983462-B1 AQUEOUS POLYMER DISPERSIONS SUITABLE AS OPACIFIERS IN LIQUID FORMULATIONS BASF SE (DE) 2025-01-08 EP disclosed
US-20220306791-A1 AQUEOUS POLYMER DISPERSIONS SUITABLE AS OPACIFIERS IN LIQUID FORMULATIONS BASF SE (DE) 2022-09-29 US disclosed
US-11427728-B2 Method for producing aqueous dispersions BASF SE (DE) 2022-08-30 US disclosed
EP-3983462-A1 AQUEOUS POLYMER DISPERSIONS SUITABLE AS OPACIFIERS IN LIQUID FORMULATIONS BASF SE (DE) 2022-04-20 EP disclosed
US-11292861-B2 Aqueous polymer dispersion BASF SE (DE) 2022-04-05 US disclosed
US-20210292457-A1 AQUEOUS POLYMER DISPERSION BASF SE (DE) 2021-09-23 US disclosed
WO-2020249706-A1 AQUEOUS POLYMER DISPERSIONS SUITABLE AS OPACIFIERS IN LIQUID FORMULATIONS BASF SE (DE) 2020-12-17 WO disclosed
EP-3523382-B1 METHOD FOR PRODUCING AQUEOUS DISPERSIONS BASF SE (DE) 2020-11-18 EP disclosed
EP-3491029-B1 AQUEOUS POLYMER DISPERSION BASF SE (DE) 2020-05-20 EP disclosed
EP-0150479-B1 PROCESS FOR MODIFYING CONJUGATED DIENE POLYMERS NIPPON ZEON CO., LTD. (JP) 1990-06-13 EP disclosed
EP-0355029-A2 Thermoplastic propylene resin composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-02-21 EP disclosed
US-4786680-A NONSKIDDING, NATURAL RUBBER, POLYISOPRENE, SBR, HALOGENATED BUTYL RUBBER THE YOKOHAMA RUBBER CO., LTD. (JP) 1988-11-22 US disclosed
US-4647625-A Process for modifying conjugated diene polymers NIPPON ZEON CO., LTD. (JP) 1987-03-03 US disclosed
EP-0150479-A2 Process for modifying conjugated diene polymers NIPPON ZEON CO., LTD. (JP) 1985-08-07 EP disclosed
EP-0062161-B1 SYNTHESIS OF AMIDES USING CARBAMIC-ACID SALTS UNION CARBIDE CORPORATION (US) 1984-08-08 EP disclosed
US-4389521-A AROMATIC POLYAMIDE TEIJIN LIMITED (JP) 1983-06-21 US disclosed
US-4379928-A Synthesis of amides UNION CARBIDE CORPORATION (US) 1983-04-12 US disclosed
EP-0062161-A1 Synthesis of amides using carbamic-acid salts UNION CARBIDE CORPORATION (US) 1982-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220306791-A1 AQUEOUS POLYMER DISPERSIONS SUITABLE AS OPACIFIERS IN LIQUID FORMULATIONS LPO, SORD, GYS1 CHRNB2 4207/4885CHRNB4 4235/4885CHRNA3 4605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.