Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.50 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211525 | 1.00 | TSHR (0.50) | TSHRCES2CES1ALDH1A1LMNA | |
| SCHEMBL7799476 | 0.97 | CES2 (0.48) | TSHRCES2CES1ALDH1A1LMNA | |
| SCHEMBL7796843 | 0.97 | CES2 (0.48) | TSHRCES2CES1ALDH1A1LMNA | |
| SCHEMBL19858906 | 0.97 | CES2 (0.48) | TSHRCES2CES1ALDH1A1LMNA | |
| SCHEMBL7799475 | 0.97 | CES2 (0.48) | TSHRCES2CES1ALDH1A1LMNA | |
| SCHEMBL7799468 | 0.97 | CES2 (0.48) | TSHRCES2CES1ALDH1A1LMNA | |
| SCHEMBL7800661 | 0.97 | CES2 (0.48) | TSHRCES2CES1ALDH1A1LMNA | |
| SCHEMBL7799457 | 0.97 | CES2 (0.48) | TSHRCES2CES1ALDH1A1LMNA | |
| SCHEMBL7796669 | 0.94 | CES2 (0.46) | TSHRCES2CES1ALDH1A1LMNA | |
| SCHEMBL7796862 | 0.85 | CES1 (0.43) | TSHRCES2CES1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153322-A | Methods for making fluorinated surface modifying agents, methods of using same and products made using same | HOUSTON, UNIVERSITY OF | 2000-11-28 | — | — | US | disclosed |
| WO-1998040169-A1 | METHODS FOR MAKING FLUORINATED SURFACE MODIFYING AGENTS, METHODS OF USING SAME AND PRODUCTS MADE USING SAME | THE UNIVERSITY OF HOUSTON (US) | 1998-09-17 | — | — | WO | disclosed |