Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211584 | 1.00 | GGT1 (0.56) | GGT1EPHX2CYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL8209005 | 0.98 | GGT1 (0.55) | GGT1EPHX2CYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL8209008 | 0.98 | GGT1 (0.55) | GGT1EPHX2CYP2D6CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL11100782 | 0.98 | GGT1 (0.55) | GGT1EPHX2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7466905 | 0.90 | CYP3A4 (0.45) | GGT1CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL7466897 | 0.90 | CYP3A4 (0.45) | GGT1CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL8054827 | 0.90 | CYP3A4 (0.45) | GGT1CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL27507226 | 0.87 | GGT1 (0.67) | GGT1EPHX2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL27507225 | 0.87 | GGT1 (0.67) | GGT1EPHX2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL4560841 | 0.87 | GGT1 (0.67) | GGT1EPHX2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114391-A | A DERIVATIVES OF SERINAMIDE, GLYCINAMIDE, ALANINAMIDE AND PHENYLALANINAMIDE FOR TREATING NEUROLOGICAL DISEASES | CHIESI FARMACEUTICI S.P.A. (IT) | 2000-09-05 | — | — | US | disclosed |