Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 13/20 | 0.73 |
| ▸ | OPRM1 | P35372 | 13/20 | 0.73 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.73 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.61 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.61 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211645 | 1.00 | OPRD1 (0.73) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL29894293 | 0.96 | OPRD1 (0.77) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL22959885 | 0.96 | OPRD1 (0.77) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL5666860 | 0.92 | OPRD1 (0.73) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL27855934 | 0.91 | OPRM1 (0.72) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL30301310 | 0.89 | OPRM1 (0.74) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL8561332 | 0.88 | OPRD1 (0.78) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL12220381 | 0.88 | OPRD1 (0.78) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 | |
| SCHEMBL8210710 | 0.88 | OPRD1 (0.70) | OPRD1OPRM1OPRK1MRGPRX2 | |
| SCHEMBL13800802 | 0.88 | OPRD1 (0.65) | OPRD1OPRM1OPRK1MRGPRX2SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6150524-A | MORPHINAN DERIVATIVES | CENES LTD. (GB) | 2000-11-21 | — | — | US | disclosed |