⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466676 | 1.00 | — | — | |
| SCHEMBL27483988 | 1.00 | — | — | |
| SCHEMBL27282487 | 0.92 | — | — | |
| SCHEMBL11233491 | 0.90 | — | — | |
| SCHEMBL27559419 | 0.85 | — | — | |
| SCHEMBL27608002 | 0.77 | NOS2 (0.33) | — | |
| SCHEMBL24097659 | 0.72 | — | — | |
| SCHEMBL1604499 | 0.72 | — | — | |
| SCHEMBL80843 | 0.72 | — | — | |
| SCHEMBL6959033 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054865-A1 | FARNESYL TRANSFERASE INHIBITORS | AstraZeneca UK Limited (GB) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999041235-A1 | FARNESYL TRANSFERASE INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-08-19 | — | — | WO | disclosed |