Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.57 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.57 |
| ▸ | GLS | O94925 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4171022 | 0.84 | STS (0.55) | ALDH1A1USP30EPHX1ACHEGPR119 | |
| SCHEMBL20267975 | 0.84 | STS (0.55) | ALDH1A1USP30EPHX1ACHEGPR119 | |
| SCHEMBL20566961 | 0.82 | TEAD1 (0.63) | CARM1PRMT6SCN9AEPHX2GPR119 | |
| SCHEMBL4574282 | 0.82 | USP30 (0.60) | ALDH1A1USP30EPHX1GPR119MCHR1 | |
| SCHEMBL22387579 | 0.82 | STS (0.48) | ALDH1A1USP30EPHX1EPHX2GPR119 | |
| SCHEMBL4244799 | 0.82 | GPR119 (0.61) | CARM1PRMT6ALDH1A1EPHX1GPR119 | |
| SCHEMBL3758709 | 0.81 | GPR119 (0.57) | ALDH1A1EPHX1BCHEACHEBACE1 | |
| SCHEMBL4210228 | 0.80 | CARM1 (0.55) | CARM1PRMT6ALDH1A1USP30EPHX1 | |
| SCHEMBL4139961 | 0.80 | STS (0.56) | CARM1PRMT6ALDH1A1EPHX1CCNT1 | |
| SCHEMBL16462875 | 0.80 | KCNH2 (0.46) | CARM1PRMT6ALDH1A1EPHX1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008065500-A2 | HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-06-05 | — | — | WO | disclosed |