Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 4/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6043670 | 0.94 | ATM (0.48) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL1711871 | 0.86 | TDP1 (0.48) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL4548026 | 0.82 | L3MBTL1 (0.71) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL12923889 | 0.82 | PAOX (0.61) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL6043600 | 0.82 | GNAI3 (0.50) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL6043595 | 0.82 | GNAI3 (0.50) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL4686342 | 0.82 | ATM (0.71) | L3MBTL1KMT2AMEN1TDP1ATM | |
| SCHEMBL294495 | 0.81 | L3MBTL1 (0.54) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL8972852 | 0.81 | GNAI3 (0.71) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL14520784 | 0.81 | KMT2A (0.57) | GNAI3GNAI1GNAO1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100262-A | MORPHOLINE RING NITROGEN IS SUBSTITUTED WITH A GROUP HAIVNG A CARBONYL FUNCTIONALITY; FAVOURABLE GASTROINTESTINAL MOTILITY STIMULATING PROPERTIES, THEY ACCELERATE GASTRIC EMPTYING | JANSSEN PHARMACEUTICA, NV. (BE) | 2000-08-08 | — | — | US | disclosed |
| EP-0827500-A1 | (2-MORPHOLINYLMETHYL)BENZAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-03-11 | — | — | EP | disclosed |
| WO-1996037486-A1 | (2-MORPHOLINYLMETHYL)BENZAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1996-11-28 | — | — | WO | disclosed |