Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.54 |
| ▸ | CA1 | P00915 | 8/20 | 0.54 |
| ▸ | CA9 | Q16790 | 5/20 | 0.54 |
| ▸ | CA7 | P43166 | 5/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212941 | 1.00 | CA2 (0.54) | CA2CA1CA9CA7CA14 | |
| SCHEMBL8212942 | 1.00 | CA2 (0.54) | CA2CA1CA9CA7CA14 | |
| SCHEMBL8207584 | 0.93 | PDE4D (0.53) | CA2CA1CA9CA7CA14 | |
| SCHEMBL8207586 | 0.93 | PDE4D (0.53) | CA2CA1CA9CA7CA14 | |
| SCHEMBL5036841 | 0.90 | PDE4D (0.53) | CA2CA1CA9CA7CA14 | |
| SCHEMBL5036837 | 0.90 | PDE4D (0.53) | CA2CA1CA9CA7CA14 | |
| SCHEMBL2881522 | 0.88 | PDE4D (0.51) | CA2CA1CA9CA7CA14 | |
| SCHEMBL2881520 | 0.88 | PDE4D (0.51) | CA2CA1CA9CA7CA14 | |
| SCHEMBL2881526 | 0.88 | PDE4D (0.51) | CA2CA1CA9CA7CA14 | |
| SCHEMBL5057778 | 0.87 | PDE4D (0.48) | CA2CA1CA9CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121279-A | PHOSPHODIESTERASE INHIBITOR FOR TREATING RESPIRATORY SYSTEM DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-09-19 | — | — | US | disclosed |