Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | REV1 | Q9UBZ9 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212725 | 0.92 | GAA (0.56) | GAAMAPTPOLBHIF1AREV1 | |
| SCHEMBL7420721 | 0.91 | POLB (0.53) | GAAMAPTPOLBHIF1AREV1 | |
| Bicarbonate SCHEMBL7889270 | 0.91 | GAA (0.52) | GAAMAPTPOLBHIF1AREV1 | |
| SCHEMBL7424975 | 0.90 | GAA (0.50) | GAAMAPTPOLBHIF1AREV1 | |
| SCHEMBL7892987 | 0.90 | GAA (0.53) | GAAMAPTPOLBHIF1AREV1 | |
| SCHEMBL7890839 | 0.87 | ALDH1A1 (0.45) | GAAMAPTPOLBHIF1AREV1 | |
| SCHEMBL7424534 | 0.87 | MAPT (0.47) | GAAMAPTPOLBHIF1AREV1 | |
| SCHEMBL7888442 | 0.86 | POLB (0.52) | GAAMAPTPOLBHIF1AREV1 | |
| SCHEMBL8200327 | 0.86 | KMT2A (0.52) | GAAMAPTPOLBHIF1AALDH1A1 | |
| SCHEMBL7892994 | 0.85 | USP2 (0.45) | MAPTNPSR1ALDH1A1USP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |