SCHEMBL8213504

SCHEMBL8213504

C=CC(c1ccccc1)C(NCCNCCC[Si](OC)(OC)OC)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 2/20 0.33
GRIN2A Q12879 2/20 0.33
SLC6A2 P23975 3/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
DRD3 P35462 1/20 0.33
PMP22 Q01453 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HTR1A P08908 1/20 0.31
ADRA1D P25100 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL645257 0.85 GRIN1 (0.35) GRIN1GRIN2ACYP3A4TSHRSIGMAR1
Hydrochloric Acid SCHEMBL1475959 0.84 ALDH1A1 (0.34) GRIN1GRIN2ACYP3A4TSHRSIGMAR1
Hydrochloric Acid SCHEMBL5894237 0.84 ALDH1A1 (0.34) GRIN1GRIN2ACYP3A4TSHRSIGMAR1
SCHEMBL1453093 0.77 ALDH1A1 (0.38) MEN1CYP3A4TSHRKMT2ASIGMAR1
SCHEMBL962275 0.77 SMN1; SMN2 (0.36) GRIN1GRIN2ASLC6A2SIGMAR1SLC6A4
Hydrochloric Acid SCHEMBL22362253 0.76 ALDH1A1 (0.40) SLC6A2MEN1CYP3A4TSHRKMT2A
SCHEMBL16894027 0.74 GRIN1 (0.34) GRIN1GRIN2ACYP3A4TSHRSIGMAR1
Hydrochloric Acid SCHEMBL2678849 0.72 HTT (0.35) GRIN1GRIN2ACYP3A4TSHRSIGMAR1
SCHEMBL2930671 0.72 HPGD (0.32) SLC6A2MEN1CYP1A2CYP3A4CYP2D6
SCHEMBL10777459 0.72 ALDH1A1 (0.34) SLC6A2MEN1CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0832945-B1 Coating agent composition and composite film DOW CORNING TORAY SILICONE (JP) 2000-05-24 EP disclosed